STAT-ERA-SEP -- All players in database
Regular season
| Primary |
| Name | Name | ERA |
| Hal Brown | Saints | 2.15 |
| Vern Law | Saints | 2.27 |
| Bill Monbouquette | Bishops | 2.34 |
| Roger Craig | Bishops | 2.53 |
| Bob Purkey | Aces | 2.59 |
| Camilo Pascual | Bishops | 2.69 |
| Gene Conley | Gladiators | 2.79 |
| Dick Donovan | Saints | 2.84 |
| Don Newcombe | Elephants | 2.85 |
| Lew Burdette | Aces | 2.91 |
| Ike Delock | Elephants | 2.94 |
| Harvey Haddix* | Slims | 2.98 |
| Gary Bell | Lakers | 3.01 |
| Jim Owens | Saints | 3.06 |
| Stu Miller | Gladiators | 3.06 |
| Jim Bunning | Surfers | 3.11 |
| Robin Roberts | Surfers | 3.17 |
| Larry Jackson | Monarchs | 3.22 |
| Jack Harshman* | Monarchs | 3.25 |
| Bob Shaw | Hot Rods | 3.27 |
| Don Mossi* | Fortress | 3.35 |
| Stan Williams | Hot Rods | 3.39 |
| Johnny Podres* | Aces | 3.48 |
| Frank Sullivan | Elephants | 3.53 |
| Dave Hillman | Beavers | 3.53 |
| Warren Spahn* | Hornets | 3.53 |
| Danny McDevitt* | Cruisers | 3.55 |
| Don Drysdale | Monarchs | 3.55 |
| Johnny Kucks | Cruisers | 3.61 |
| Hoyt Wilhelm | Hornets | 3.65 |
| Joey Jay | Gladiators | 3.69 |
| Billy O'Dell* | Aces | 3.72 |
| Mike McCormick* | Lakers | 3.74 |
| Early Wynn | Elephants | 3.75 |
| Whitey Ford* | Cruisers | 3.75 |
| Jim Perry | Fortress | 3.76 |
| Jerry Walker | Hornets | 3.78 |
| Paul Foytack | Lakers | 3.80 |
| Frank Lary | Fortress | 3.85 |
| Billy Pierce* | Hornets | 3.87 |
| Ned Garver | Beavers | 3.87 |
| Ralph Terry | Fortress | 3.91 |
| Duke Maas | Slims | 3.93 |
| Pedro Ramos | Cruisers | 3.96 |
| Sam Jones | Monarchs | 3.97 |
| Ronnie Kline | Hot Rods | 4.04 |
| Bill Fischer | Beavers | 4.10 |
| Brooks Lawrence | Slims | 4.10 |
| Johnny Antonelli* | Fortress | 4.12 |
| Don Cardwell | Hot Rods | 4.14 |
| Glen Hobbie | Hot Rods | 4.17 |
| Carlton Willey | Surfers | 4.18 |
| Wilmer Mizell* | Surfers | 4.21 |
| Bob Friend | Elephants | 4.24 |
| Bud Daley* | Beavers | 4.24 |
| Cal McLish | Gladiators | 4.28 |
| Joe Nuxhall* | Hornets | 4.34 |
| Bob Anderson | Gladiators | 4.37 |
| Bob Buhl | Slims | 4.52 |
| Jay Hook | Cruisers | 4.54 |
| Herb Score* | Hot Rods | 4.63 |
| Milt Pappas | Monarchs | 4.66 |
| Art Ditmar | Bishops | 4.71 |
| Art Ceccarelli* | Gladiators | 4.84 |
| Jim O'Toole* | Hot Rods | 4.97 |
| Jerry Casale | Bishops | 5.01 |
| John Tsitouris | Lakers | 5.07 |
| Bob Turley | Surfers | 5.12 |
| Jack Sanford | Slims | 5.23 |
| Sandy Koufax* | Bishops | 5.30 |
| Johnny Buzhardt | Lakers | 5.32 |
| Mudcat Grant | Surfers | 5.96 |