| Name | Name | K |
| Nolan Ryan | Dragons | 269 |
| Tom Seaver | Gladiators | 216 |
| Bert Blyleven | Gladiators | 210 |
| Joe Coleman | Lions | 157 |
| Luis Tiant | Gladiators | 149 |
| Jon Matlack* | Royals | 146 |
| Don Sutton | Monarchs | 146 |
| Ferguson Jenkins | Sparkplugs | 138 |
| Jim Bibby | Fortress | 134 |
| Andy Messersmith | Fortress | 133 |
| Rudy May* | Gladiators | 130 |
| Don Gullett* | Elephants | 129 |
| Steve Carlton* | Hot Rods | 125 |
| Rick Reuschel | Angels | 121 |
| Vida Blue* | Hot Rods | 119 |
| Fred Norman* | Elephants | 119 |
| Gaylord Perry | Totems | 118 |
| Bob Gibson | Beavers | 117 |
| Ken Holtzman* | Sparkplugs | 116 |
| Rick Wise | Bishops | 114 |
| Wayne Twitchell | Fortress | 114 |
| Don Wilson | Colts | 112 |
| Bill Singer | Schema Busters | 111 |
| Steve Renko | Royals | 109 |
| Jim Palmer | Hot Rods | 108 |
| Reggie Cleveland | Mets | 108 |
| Ken Forsch | Barons | 108 |
| Clay Kirby | Dragons | 108 |
| Jack Billingham | Cruisers | 107 |
| Bill Lee* | Barons | 105 |
| Al Downing* | Elephants | 105 |
| Jerry Reuss* | Sparkplugs | 105 |
| Jerry Koosman* | Mets | 103 |
| John Curtis* | Colts | 99 |
| Jim Rooker* | Royals | 98 |
| Brent Strom* | Seagulls | 97 |
| Dock Ellis | Monarchs | 97 |
| Tom Bradley | Fortress | 96 |
| Wilbur Wood* | Totems | 94 |
| Steve Stone | Gladiators | 93 |
| Dick Ruthven | Monarchs | 93 |
| Steve Busby | Totems | 92 |
| Doc Medich | Cruisers | 91 |
| Ken Brett* | Seals | 89 |
| Burt Hooton | Royals | 86 |
| Jim Slaton | Beavers | 85 |
| Nelson Briles | Elephants | 85 |
| Phil Niekro | Mets | 85 |
| Ron Schueler | Dragons | 85 |
| Jim Kaat* | Sparkplugs | 85 |
| Marty Pattin | Seagulls | 84 |
| Mickey Lolich* | Totems | 83 |
| Tommy John* | Seals | 83 |
| Sam McDowell* | Seals | 83 |
| Stan Bahnsen | Lions | 82 |
| Paul Splittorff* | Dragons | 81 |
| Ross Grimsley* | Bishops | 81 |
| Bill Bonham | Angels | 80 |
| Joe Decker | Barons | 79 |
| Jim Colborn | Dragons | 78 |
| Roric Harrison | Colts | 78 |
| Woodie Fryman* | Angels | 77 |
| Ron Bryant* | Monarchs | 75 |
| Bob Moose | Mets | 74 |
| Pat Dobson | Lions | 74 |
| Jim Hunter | Hot Rods | 73 |
| Balor Moore* | Monarchs | 73 |
| Jim Lonborg | Monarchs | 72 |
| Blue Moon Odom | Cruisers | 71 |
| Carl Morton | Schema Busters | 71 |
| Randy Jones* | Seagulls | 71 |
| Steve Arlin | Seagulls | 70 |
| Dave Goltz | Seals | 69 |
| Mike Cuellar* | Totems | 68 |
| Dave McNally* | Fortress | 68 |
| Dick Tidrow | Elephants | 68 |
| Dave Roberts* | Barons | 67 |
| Rich Troedson* | Seals | 65 |
| Jerry Bell | Bishops | 64 |
| Diego Segui | Totems | 64 |
| Mike Torrez | Bishops | 63 |
| J.R. Richard | Seals | 63 |
| Jim Perry | Angels | 61 |
| Juan Marichal | Beavers | 61 |
| Dick Drago | Barons | 60 |
| Alan Foster | Hot Rods | 59 |
| Mike Marshall | Hot Rods | 59 |
| Roger Moret* | Monarchs | 58 |
| Rollie Fingers | Hot Rods | 58 |
| Ray Corbin | Seals | 58 |
| Eddie Fisher | Schema Busters | 58 |
| Doyle Alexander | Elephants | 57 |
| Mel Stottlemyre | Cruisers | 57 |
| Steve Barber* | Schema Busters | 57 |
| John Hiller* | Gladiators | 56 |
| Clyde Wright* | Colts | 56 |
| Sonny Siebert | Colts | 56 |
| Doug Bird | Angels | 55 |
| Tug McGraw* | Hot Rods | 55 |
| Claude Osteen* | Schema Busters | 55 |
| Bob Reynolds | Fortress | 54 |
| Lindy McDaniel | Totems | 54 |
| Terry Forster* | Dragons | 54 |
| Bill Greif | Monarchs | 53 |
| Elias Sosa | Lions | 52 |
| Orlando Pena | | 52 |
| Milt Wilcox | Angels | 51 |
| Jim Merritt* | Colts | 50 |
| Bill Gogolewski | Beavers | 50 |
| Charlie Hough | Bishops | 50 |
| Ray Sadecki* | Totems | 49 |
| Bob Locker | Cruisers | 49 |
| Mac Scarce* | Angels | 49 |
| Doug Rau* | Seagulls | 49 |
| Steve Mingori* | Monarchs | 49 |
| Mike Paul* | Seals | 49 |
| Ken Wright | Cruisers | 48 |
| Bob Johnson | Lions | 48 |
| Jesse Jefferson | Beavers | 47 |
| David Clyde* | Lions | 47 |
| Al Hrabosky* | Angels | 47 |
| Milt Pappas | Seals | 47 |
| Tom Timmermann | Angels | 47 |
| Skip Lockwood | Royals | 46 |
| Darold Knowles* | Beavers | 46 |
| Gene Garber | Lions | 45 |
| Mike Corkins | Beavers | 45 |
| George Stone* | | 44 |
| Bob Miller | Sparkplugs | 44 |
| Don Stanhouse | Seals | 43 |
| Tom Walker | Beavers | 43 |
| Tom Hall* | Colts | 43 |
| Ernie McAnally | | 42 |
| Mike Caldwell* | Mets | 41 |
| Fritz Peterson* | Seagulls | 40 |
| Jim McAndrew | Bishops | 40 |
| Dick Bosman | Lions | 40 |
| Rich Hand | Bishops | 40 |
| Jerry Johnson | Schema Busters | 39 |
| Dave Giusti | Monarchs | 39 |
| Randy Moffitt | Schema Busters | 39 |
| Steve Dunning | Schema Busters | 39 |
| Dick Pole | Royals | 37 |
| Eduardo Rodriguez | Colts | 37 |
| Dick Woodson | Angels | 37 |
| Ray Burris | Schema Busters | 37 |
| Grant Jackson* | Beavers | 36 |
| Pedro Borbon | Angels | 36 |
| Don Carrithers | Mets | 36 |
| Ray Lamb | Sparkplugs | 35 |
| Dave Hamilton* | Cruisers | 35 |
| Jim Barr | Fortress | 35 |
| Gary Gentry | Beavers | 35 |
| Jim Willoughby | Mets | 34 |
| Chris Short* | Beavers | 33 |
| Bill Campbell | Royals | 33 |
| Bart Johnson | Totems | 33 |
| Ron Reed | Cruisers | 33 |
| Bobby Bolin | | 32 |
| Lerrin LaGrow | Barons | 32 |
| Bill Champion | Barons | 32 |
| Bill Hands | Dragons | 31 |
| Fred Beene | Elephants | 30 |
| Tom Hilgendorf* | Lions | 30 |
| Harry Parker | | 30 |
| Cy Acosta | Gladiators | 28 |
| Rich Folkers* | Totems | 28 |
| John D'Acquisto | Dragons | 28 |
| Tom Griffin | Barons | 28 |
| Al Fitzmorris | Totems | 27 |
| Bill Parsons | Seagulls | 26 |
| Paul Lindblad* | Lions | 26 |
| Bill Stoneman | Lions | 26 |
| Vicente Romo | | 26 |
| Sparky Lyle* | Hot Rods | 25 |
| Steve Rogers | Mets | 25 |
| Jim McGlothlin | Schema Busters | 25 |
| Pete Broberg | Barons | 24 |
| John Morlan | Seagulls | 24 |
| Dick Baney | Dragons | 24 |
| Don McMahon | Colts | 24 |
| Joe Hoerner* | Seagulls | 24 |
| Wayne Simpson | Colts | 23 |
| Dick Lange | Schema Busters | 23 |
| Ramon Hernandez* | Gladiators | 23 |
| Pete Richert* | Barons | 23 |
| Bob Veale* | Bishops | 22 |
| Pat Jarvis | Monarchs | 22 |
| Jim Crawford* | Barons | 22 |
| Ed Farmer | | 22 |
| Danny Fife | Beavers | 21 |
| Eddie Bane* | Lions | 21 |
| Barry Lersch | Totems | 21 |
| Wayne Granger | Cruisers | 21 |
| Lloyd Allen | Schema Busters | 21 |
| Cecil Upshaw | Seagulls | 21 |
| Bruce Dal Canton | Fortress | 20 |
| Tom Murphy | Dragons | 20 |
| Mike Kekich* | | 20 |
| Craig Skok* | Lions | 19 |
| Goose Gossage | Sparkplugs | 19 |
| Jackie Brown | Barons | 19 |
| Buzz Capra | Angels | 19 |
| Ken Sanders | Sparkplugs | 19 |
| Frank Tanana* | Colts | 18 |
| Don Durham | Schema Busters | 18 |
| Jim Brewer* | Gladiators | 18 |
| Mike Strahler | Colts | 16 |
| Fred Scherman* | Colts | 16 |
| Steve Foucault | Fortress | 16 |
| Jack Aker | Royals | 16 |
| Larry Gura* | Royals | 16 |
| George Culver | Seagulls | 16 |
| Dave LaRoche* | Royals | 15 |
| Jim Ray | Bishops | 15 |
| Max Leon | Barons | 15 |
| Don Hood* | Sparkplugs | 14 |
| Ron Diorio | Elephants | 14 |
| Horacio Pina | Elephants | 13 |
| Joe Gilbert* | Seagulls | 13 |
| Jim York | | 13 |
| Ed Sprague | Lions | 13 |
| Eddie Watt | Hot Rods | 12 |
| Lynn McGlothen | Angels | 12 |
| Steve Kline | Seagulls | 12 |
| Aurelio Monteagudo | Gladiators | 12 |
| Charlie Hudson* | Hot Rods | 12 |
| Bruce Kison | Mets | 12 |
| Chuck Taylor | Mets | 12 |
| Larry Dierker | Colts | 12 |
| Tom House* | Gladiators | 12 |
| John Strohmayer | Bishops | 12 |
| Andy Hassler* | Colts | 11 |
| Mike Garman | Mets | 11 |
| Roger Nelson | Gladiators | 11 |
| Luke Walker* | Hot Rods | 10 |
| Greg Shanahan | Elephants | 10 |
| Frank Snook | | 10 |
| Bucky Brandon | Barons | 9 |
| Adrian Devine | Elephants | 9 |
| Gary Ross | Barons | 9 |
| Mickey Scott* | | 9 |
| Chuck Seelbach | Sparkplugs | 8 |
| Carlos Velazquez | Angels | 8 |
| Dave Sells | Beavers | 8 |
| Dennis O'Toole | Beavers | 8 |
| Phil Hennigan | Monarchs | 8 |
| Tom Dettore | Seals | 8 |
| Mike Wallace* | Cruisers | 8 |
| Clay Carroll | Fortress | 8 |
| Charlie Williams | Schema Busters | 8 |
| Danny Frisella | Gladiators | 8 |
| Mike Jackson* | Beavers | 8 |
| Vic Albury* | Cruisers | 7 |
| Rick Henninger | Colts | 7 |
| Dave Tomlin* | Sparkplugs | 7 |
| Jim Magnuson* | Cruisers | 6 |
| Frank Linzy | Dragons | 6 |
| Jim McKee | Colts | 6 |
| Wayne Garland | Elephants | 5 |
| Ray Culp | Barons | 5 |
| Kevin Kobel* | Mets | 5 |
| Ken Reynolds* | Monarchs | 5 |
| Al Santorini | Beavers | 5 |
| Steve Blass | Seagulls | 5 |
| Tom Kelley | Beavers | 5 |
| Ray Newman* | Elephants | 4 |
| Mark Littell | Cruisers | 4 |
| Geoff Zahn* | Hot Rods | 4 |
| Eddie Solomon | Seagulls | 4 |
| Mike Cosgrove* | Seals | 4 |
| Jimmy Freeman* | Seagulls | 4 |
| Fred Holdsworth | Dragons | 3 |
| Glenn Abbott | Schema Busters | 3 |
| Chris Zachary | Barons | 3 |
| Wenty Ford | Beavers | 3 |
| Mike Nagy | Dragons | 3 |
| Don Newhauser | Monarchs | 2 |
| John Lamb | Schema Busters | 2 |
| Jim Panther | Schema Busters | 2 |
| Joe Niekro | Royals | 2 |
| Bill Slayback | Seals | 1 |
| Mike Thompson | Monarchs | 1 |
| Dave Pagan | Beavers | 1 |
| Jim Geddes | Totems | 1 |
| Craig Caskey* | Seals | 1 |
| John Andrews* | | 0 |
| Craig Swan | Royals | 0 |
| Dick Selma | Monarchs | 0 |
| Doug Konieczny | Bishops | 0 |
| Juan Pizarro* | Beavers | 0 |