| Name | Name | K |
| Billy Pierce* | Arsenal | 220 |
| Carl Erskine | Thunderbolts | 201 |
| Wilmer Mizell* | Blues | 187 |
| Harvey Haddix* | Tigers | 181 |
| Warren Spahn* | Stampers | 164 |
| Robin Roberts | Muck Dogs | 159 |
| Johnny Antonelli* | Tigers | 152 |
| Mike Garcia | Grays | 149 |
| Virgil Trucks | Muck Dogs | 146 |
| Ted Gray* | Grays | 143 |
| Mel Parnell* | Tigers | 142 |
| Whitey Ford* | Larks | 122 |
| Bob Lemon | Carp | 120 |
| Ruben Gomez | Hawks | 116 |
| Curt Simmons* | Larks | 115 |
| Mickey McDermott* | Clowns | 115 |
| Early Wynn | Rugrats | 114 |
| Walt Masterson | | 101 |
| Roger Bowman* | Aces | 98 |
| Larry Jansen | Hawks | 97 |
| Vic Raschi | Arsenal | 94 |
| Johnny Sain | | 94 |
| Bob Rush | Carp | 92 |
| Max Surkont | Thunderbolts | 86 |
| Harry Byrd | Tigers | 84 |
| Warren Hacker | Stampers | 83 |
| Connie Marrero | Blues | 81 |
| Bob Friend | Clowns | 80 |
| Jim Hearn | Grays | 80 |
| Johnny Podres* | Rugrats | 80 |
| Don Larsen | Arsenal | 80 |
| Alex Kellner* | Clowns | 80 |
| Bob Buhl | Larks | 78 |
| Preacher Roe* | Rugrats | 78 |
| Bob Porterfield | Stampers | 78 |
| Morrie Martin* | Royal Giants | 76 |
| Paul LaPalme* | Clowns | 75 |
| Joe Nuxhall* | Grays | 74 |
| Don Liddle* | Blues | 74 |
| Chuck Stobbs* | Larks | 74 |
| Marv Grissom | Tigers | 74 |
| Steve Gromek | Grays | 74 |
| Murry Dickson | | 73 |
| Paul Minner* | Stampers | 73 |
| Gerry Staley | Clowns | 73 |
| Bob Milliken | Grays | 73 |
| Eddie Lopat* | Thunderbolts | 73 |
| Bobby Shantz* | Stampers | 72 |
| Johnny Klippstein | Rugrats | 71 |
| Sal Maglie | Stampers | 71 |
| Johnny Lindell | Carp | 71 |
| Dave Hoskins | Blues | 70 |
| Harry Perkowski* | Royal Giants | 69 |
| Marion Fricano | Arsenal | 69 |
| Jackie Collum* | Aces | 69 |
| Turk Lown | Larks | 68 |
| Bud Podbielan | Larks | 68 |
| Allie Reynolds | Hawks | 67 |
| Billy Hoeft* | Arsenal | 66 |
| Ned Garver | Larks | 66 |
| Willard Nixon | Clowns | 66 |
| Bob Feller | Rugrats | 65 |
| Ben Wade | Thunderbolts | 64 |
| Bob Turley | Royal Giants | 63 |
| Hal Brown | Muck Dogs | 63 |
| Saul Rogovin | Royal Giants | 63 |
| Ralph Branca | Thunderbolts | 63 |
| Russ Meyer | Hawks | 62 |
| Harry Brecheen* | Stampers | 62 |
| Bob Hall | Royal Giants | 61 |
| Joe Presko | Aces | 61 |
| Mike Fornieles | Carp | 61 |
| Hoyt Wilhelm | Aces | 58 |
| Ken Raffensberger* | Blues | 57 |
| Bill Henry* | Hawks | 57 |
| Duane Pillette | Aces | 56 |
| Dick Littlefield* | Rugrats | 55 |
| Joe Dobson | Carp | 54 |
| Jim McDonald | Blues | 54 |
| Harry Dorish | Arsenal | 51 |
| Bob Kuzava* | Muck Dogs | 51 |
| Billy Loes | Hawks | 50 |
| Bob Cain* | Royal Giants | 50 |
| Sandy Consuegra | Blues | 50 |
| Bubba Church | Royal Giants | 48 |
| Johnny Schmitz* | Muck Dogs | 48 |
| Ray Herbert | Royal Giants | 46 |
| Jim Wilson | Tigers | 45 |
| Art Houtteman | Arsenal | 45 |
| Clem Labine | Hawks | 44 |
| Sid Hudson | Arsenal | 44 |
| Jim Hughes | Clowns | 43 |
| Al Brazle* | Arsenal | 42 |
| Stu Miller | Carp | 42 |
| Luis Aloma | Aces | 41 |
| Tom Gorman | Hawks | 41 |
| Cliff Chambers* | Muck Dogs | 40 |
| Bob Miller | Muck Dogs | 40 |
| Dave Koslo* | Thunderbolts | 39 |
| Lew Burdette | Rugrats | 39 |
| Frank Fanovich* | Muck Dogs | 39 |
| Connie Johnson | Grays | 39 |
| Howie Pollet* | Tigers | 39 |
| Charlie Bishop | Carp | 38 |
| Steve Ridzik | Clowns | 37 |
| Spec Shea | Thunderbolts | 36 |
| Ben Flowers | | 36 |
| Ernie Johnson | Arsenal | 35 |
| Kent Peterson* | Aces | 33 |
| Karl Drews | Rugrats | 33 |
| Dick Marlowe | Carp | 33 |
| Tommy Byrne* | Royal Giants | 33 |
| Joe Black | Thunderbolts | 31 |
| Sonny Dixon | Hawks | 31 |
| Bob Kelly | Aces | 31 |
| Al Aber* | Clowns | 31 |
| Roy Face | Carp | 30 |
| Frank Smith | Grays | 30 |
| Jim Konstanty | Carp | 30 |
| Satchel Paige | Hawks | 30 |
| Jerry Lane | Thunderbolts | 30 |
| Fred Baczewski* | Stampers | 29 |
| Herm Wehmeier | | 28 |
| Carl Scheib | Royal Giants | 28 |
| Ike Delock | Larks | 28 |
| Al Worthington | Muck Dogs | 27 |
| Al Corwin | Tigers | 27 |
| Dave Jolly | Thunderbolts | 27 |
| Hal Erickson | Blues | 27 |
| Bill Wight* | Tigers | 27 |
| Gene Bearden* | Clowns | 26 |
| Joe Coleman | Tigers | 25 |
| Ellis Kinder | Blues | 25 |
| Johnny Hetki | Carp | 24 |
| Bobo Holloman | Grays | 24 |
| Bob Keegan | Clowns | 24 |
| Duke Simpson | Muck Dogs | 23 |
| Vern Bickford | Royal Giants | 23 |
| Al Sima* | Tigers | 23 |
| Dave Madison | Grays | 22 |
| Mike Blyzka | Rugrats | 21 |
| Art Schallock* | Aces | 21 |
| Lou Kretlow | Tigers | 21 |
| Bob Schultz* | Rugrats | 20 |
| Jim Willis | Stampers | 19 |
| Dave Cole | Rugrats | 19 |
| Dutch Leonard | Rugrats | 18 |
| Ray Scarborough | Larks | 18 |
| Sheldon Jones | Aces | 17 |
| Marlin Stuart | Carp | 17 |
| Bill Miller* | Stampers | 17 |
| Max Lanier* | Grays | 17 |
| Hal Newhouser* | Thunderbolts | 16 |
| Frank Sullivan | Tigers | 16 |
| Andy Hansen | Rugrats | 15 |
| Julio Moreno | Blues | 15 |
| Hal White | Stampers | 15 |
| Jim Waugh | | 14 |
| Willard Schmidt | Royal Giants | 14 |
| Ewell Blackwell | Blues | 13 |
| Frank Hiller | Aces | 12 |
| Clyde King | | 11 |
| Bobo Newsom | Blues | 11 |
| Cal Hogue | Muck Dogs | 10 |
| Don Elston | Aces | 10 |
| Bill Kennedy* | Stampers | 10 |
| Earl Harrist | | 10 |
| Ernie Nevel | Thunderbolts | 9 |
| Mike Clark | Royal Giants | 9 |
| Thornton Kipper | Blues | 9 |
| Bob Hooper | Larks | 9 |
| Monte Kennedy* | Rugrats | 8 |
| Bill Connelly | Muck Dogs | 8 |
| Dean Stone* | Clowns | 8 |
| Howie Judson | Arsenal | 7 |
| Ray Moore | Aces | 7 |
| Walt Kellner | Aces | 7 |
| Bob Trice | Royal Giants | 7 |
| Paul Foytack | Royal Giants | 7 |
| Hersh Freeman | Blues | 7 |
| Bob Chakales | Rugrats | 7 |
| Dick Rozek* | Blues | 6 |
| Woody Main | Aces | 5 |
| Milt Jordan | Grays | 5 |
| Bob Miller* | Clowns | 5 |
| Steve Kraly* | | 5 |
| Eddie Erautt | Blues | 5 |
| Erv Palica | Hawks | 4 |
| Dick Tomanek* | Carp | 4 |
| Bob Habenicht | Aces | 3 |
| Rinty Monahan | Aces | 3 |
| Dick Weik | Muck Dogs | 3 |
| Ken Holcombe | | 3 |
| Lou Brissie* | Arsenal | 3 |
| Virgil Jester | Tigers | 2 |
| Joey Jay | Larks | 2 |
| Glenn Mickens | Grays | 2 |
| Fred Hutchinson | Hawks | 2 |
| Bunky Stewart* | Larks | 2 |
| Ted Wilks | Aces | 2 |
| Paul Pettit* | Blues | 1 |
| George Spencer | Muck Dogs | 1 |
| John Romonosky | Muck Dogs | 1 |
| Jim Pearce | Aces | 1 |
| Bill Werle* | Tigers | 1 |
| Bill Moisan | | 0 |
| Dick Bokelmann | Hawks | 0 |
| Tom Qualters | Carp | 0 |
| Bill Harrington | Arsenal | 0 |