| Name | Name | HR |
| Eddie Mathews* | Walleye | 22 |
| Ray Boone | Thunderbolts | 20 |
| Ted Kluszewski* | Muck Dogs | 19 |
| Hank Aaron | Walleye | 18 |
| Willie Mays | Muck Dogs | 17 |
| Dale Long* | Royal Giants | 13 |
| Larry Doby* | Aces | 12 |
| Charlie Maxwell* | Muck Dogs | 12 |
| Stan Musial* | Aces | 12 |
| Minnie Minoso | Aces | 11 |
| Ted Williams* | Walleye | 11 |
| Ed Bailey* | Aces | 10 |
| Jim Lemon | Aces | 10 |
| Roy Sievers | Larks | 10 |
| Harry Simpson* | Muck Dogs | 10 |
| Ernie Banks | Royal Giants | 9 |
| Yogi Berra* | Walleye | 9 |
| Del Ennis | Aces | 9 |
| Al Kaline | Royal Giants | 9 |
| Gil McDougald | Muck Dogs | 9 |
| Bob Nieman | Thunderbolts | 9 |
| Billy Klaus* | Aces | 8 |
| Marv Blaylock* | Carp | 7 |
| Jim Piersall | Thunderbolts | 7 |
| Jim Pisoni | Thunderbolts | 7 |
| Jackie Brandt | Larks | 7 |
| Billy Gardner | Larks | 6 |
| Ray Jablonski | Aces | 6 |
| Bob Thurman* | Thunderbolts | 6 |
| Gene Woodling* | Royal Giants | 6 |
| Richie Ashburn* | Royal Giants | 5 |
| Dick Gernert | Walleye | 5 |
| Monte Irvin | Thunderbolts | 5 |
| Jackie Jensen | Carp | 5 |
| Vic Power | Larks | 5 |
| Daryl Spencer | Muck Dogs | 5 |
| Earl Torgeson* | Royal Giants | 5 |
| Ray Katt | Aces | 5 |
| George Kell | Carp | 5 |
| Pete Daley | Royal Giants | 4 |
| Harvey Kuenn | Larks | 4 |
| Andy Seminick | Larks | 4 |
| Tim Thompson* | Thunderbolts | 4 |
| Elmer Valo* | Walleye | 4 |
| Preston Ward* | Carp | 4 |
| Gene Baker | Walleye | 3 |
| Jim Busby | Carp | 3 |
| Billy Goodman* | Carp | 3 |
| Johnny Groth | Walleye | 3 |
| Frank House* | Larks | 3 |
| Harmon Killebrew | Royal Giants | 3 |
| Billy Martin | Thunderbolts | 3 |
| Sam Mele | Thunderbolts | 3 |
| Ron Northey* | Thunderbolts | 3 |
| Andy Pafko | Thunderbolts | 3 |
| Herb Plews* | Carp | 3 |
| Bill Tuttle | Larks | 3 |
| Lee Walls | Larks | 3 |
| Hank Bauer | Walleye | 2 |
| Chico Carrasquel | Aces | 2 |
| Roberto Clemente | Larks | 2 |
| Jack Dittmer* | Thunderbolts | 2 |
| Walt Dropo | Walleye | 2 |
| Jim Gilliam# | Aces | 2 |
| Eddie Miksis | Thunderbolts | 2 |
| Willie Miranda# | Walleye | 2 |
| Les Moss | Larks | 2 |
| Stan Palys | Carp | 2 |
| Jack Shepard | Muck Dogs | 2 |
| Hank Thompson* | Muck Dogs | 2 |
| Bobby Thomson | Larks | 2 |
| Gus Triandos | Thunderbolts | 2 |
| Red Wilson | Royal Giants | 2 |
| Toby Atwell* | Walleye | 2 |
| Fred Hatfield* | Larks | 2 |
| Solly Hemus* | Royal Giants | 2 |
| Enos Slaughter* | Thunderbolts | 2 |
| Luis Aparicio | Larks | 1 |
| Earl Averill | Thunderbolts | 1 |
| Nellie Fox* | Larks | 1 |
| Bob Hale* | Walleye | 1 |
| Granny Hamner | Royal Giants | 1 |
| Jim King* | Aces | 1 |
| Hal Naragon* | Carp | 1 |
| Karl Olson | Royal Giants | 1 |
| Phil Rizzuto | Carp | 1 |
| Bob Skinner* | Royal Giants | 1 |
| Hank Foiles | Carp | 1 |
| Bob Kennedy | Carp | 1 |
| Bobby Morgan | Carp | 1 |
| Bill Virdon* | Larks | 1 |
| Clete Boyer | Royal Giants | 0 |
| Don Buddin | Aces | 0 |
| Tommy Carroll | Aces | 0 |
| Foster Castleman | Carp | 0 |
| Wayne Causey* | Muck Dogs | 0 |
| Dick Cole | Royal Giants | 0 |
| Walker Cooper | Muck Dogs | 0 |
| Wes Covington* | Larks | 0 |
| Sammy Esposito | Aces | 0 |
| Ed Fitz Gerald | Muck Dogs | 0 |
| Carl Furillo | Muck Dogs | 0 |
| Dick Groat | Muck Dogs | 0 |
| Ron Jackson | Muck Dogs | 0 |
| Ted Kazanski | Walleye | 0 |
| Jerry Lumpe* | Muck Dogs | 0 |
| Lyle Luttrell | Carp | 0 |
| Felix Mantilla | Thunderbolts | 0 |
| Johnny O'Brien | Walleye | 0 |
| Rance Pless | Walleye | 0 |
| Jim Pyburn | Carp | 0 |
| Pee Wee Reese | Thunderbolts | 0 |
| Bill Renna | Walleye | 0 |
| Tony Roig | Aces | 0 |
| Bob Roselli | Muck Dogs | 0 |
| Norm Siebern* | Larks | 0 |
| Roy Smalley | Muck Dogs | 0 |
| Walt Streuli | Muck Dogs | 0 |
| Frank Torre* | Muck Dogs | 0 |
| Wes Westrum | Muck Dogs | 0 |
| Sammy White | Carp | 0 |
| Norm Zauchin | Thunderbolts | 0 |
| Jim Brideweser | Walleye | 0 |
| Jim Dyck | Carp | 0 |
| Chuck Harmon | Aces | 0 |
| Grady Hatton* | Royal Giants | 0 |
| Dave Pope* | Thunderbolts | 0 |