| Name | Name | ERA |
| Roger Clemens | Phantoms | 1.78 |
| Greg W. Harris | Lemurs | 1.83 |
| Bill Wegman | Aviators | 2.09 |
| Nolan Ryan | Plainsmen | 2.11 |
| Matt Young* | Mud Hens | 2.13 |
| Andy Benes | Phantoms | 2.24 |
| Juan Guzman | Pachyderms | 2.32 |
| Orel Hershiser | Plainsmen | 2.42 |
| Tom Glavine* | Lemurs | 2.54 |
| Dennis Martinez | Aviators | 2.56 |
| Pete Harnisch | Phantoms | 2.58 |
| Zane Smith* | Vaqueros | 2.59 |
| Jack Morris | Grays | 2.63 |
| Mark Langston* | Lemurs | 2.72 |
| Jimmy Key* | Gnomes | 2.73 |
| Charlie Hough | Guardians | 2.76 |
| Chris Bosio | Rockets | 2.80 |
| Kevin Tapani | Phantoms | 2.81 |
| Mike Bielecki | Yard Goats | 2.81 |
| Tom Gordon | Guardians | 2.86 |
| Mark Leiter | Grays | 2.86 |
| Jose Rijo | Damage | 2.90 |
| Jim Abbott* | Grays | 2.91 |
| Mike Morgan | Plainsmen | 2.95 |
| Jose Guzman | Vaqueros | 2.96 |
| Rick Sutcliffe | Rockets | 2.98 |
| Charlie Leibrandt* | Rockets | 2.99 |
| Allan Anderson* | Game Sox | 3.00 |
| Scott Erickson | Gnomes | 3.00 |
| Bill Gullickson | SpaceMen | 3.02 |
| Scott Sanderson | Metropolitans | 3.05 |
| Steve Avery* | SpaceMen | 3.07 |
| Bobby Ojeda* | Aviators | 3.11 |
| Brian Holman | Aviators | 3.21 |
| Kevin Appier | Rough Riders | 3.21 |
| Greg Harris | Mud Hens | 3.23 |
| Greg Maddux | Game Sox | 3.23 |
| Ramon Martinez | Phantoms | 3.27 |
| Bob Tewksbury | Guardians | 3.28 |
| Greg Swindell* | Guardians | 3.33 |
| Greg Hibbard* | Grays | 3.35 |
| Bob Walk | Rough Riders | 3.35 |
| Bret Saberhagen | Firebugs | 3.36 |
| Tom Candiotti | Gnomes | 3.39 |
| Frank Tanana* | Firebugs | 3.41 |
| Bryn Smith | Pachyderms | 3.43 |
| Randy Tomlin* | Mud Hens | 3.46 |
| David West* | Zoo Crew | 3.48 |
| Chris Nabholz* | Magpies | 3.50 |
| Tommy Greene | Brushbacks | 3.52 |
| Alex Fernandez | Vaqueros | 3.56 |
| Mike Boddicker | Game Sox | 3.59 |
| Jack McDowell | Firebugs | 3.61 |
| Terry Mulholland* | Brushbacks | 3.61 |
| Mark Gardner | Canaries | 3.64 |
| Jose DeJesus | Millers | 3.67 |
| Trevor Wilson* | Rockets | 3.70 |
| Jose DeLeon | Aviators | 3.73 |
| Eric King | Grays | 3.73 |
| Todd Stottlemyre | Pachyderms | 3.74 |
| Jaime Navarro | Mud Hens | 3.75 |
| Kelly Downs | Yard Goats | 3.75 |
| Dennis Rasmussen* | Yard Goats | 3.78 |
| Mark Gubicza | Game Sox | 3.82 |
| Mike Gardiner | Brushbacks | 3.83 |
| Ben McDonald | Zoo Crew | 3.84 |
| Omar Olivares | Zoo Crew | 3.86 |
| Tim Belcher | Metropolitans | 3.86 |
| Darryl Kile | Firebugs | 3.89 |
| Jimmy Jones | Rough Riders | 3.89 |
| David Cone | Metropolitans | 3.89 |
| Jim Deshaies* | Damage | 3.92 |
| Mike Moore | Magpies | 3.96 |
| John Burkett | SpaceMen | 3.96 |
| Walt Terrell | Yard Goats | 3.99 |
| Kirk McCaskill | Damage | 4.00 |
| John Smoltz | Brushbacks | 4.02 |
| Danny Cox | Zoo Crew | 4.04 |
| Randy Johnson* | Rough Riders | 4.05 |
| Jack Armstrong | Gnomes | 4.05 |
| Mark Portugal | Lemurs | 4.06 |
| Dwight Gooden | Plainsmen | 4.08 |
| Ed Whitson | Rockets | 4.15 |
| John Smiley* | Kingsmen | 4.26 |
| Frank Viola* | Plainsmen | 4.31 |
| Ron Darling | Magpies | 4.32 |
| Bruce Hurst* | Yard Goats | 4.36 |
| Bud Black* | Guardians | 4.36 |
| Bill Krueger* | Zoo Crew | 4.42 |
| Tom Browning* | Canaries | 4.43 |
| Chuck Finley* | Vaqueros | 4.46 |
| Dave Stewart | Game Sox | 4.54 |
| Doug Drabek | SpaceMen | 4.55 |
| Bob Milacki | Kingsmen | 4.58 |
| Ken Hill | Magpies | 4.60 |
| David Wells* | Kingsmen | 4.68 |
| Danny Jackson* | Millers | 4.76 |
| Bob Welch | Firebugs | 4.79 |
| Erik Hanson | Canaries | 4.80 |
| Joe Hesketh* | Magpies | 4.82 |
| Kevin Brown | Damage | 4.86 |
| Jeff Johnson* | Zoo Crew | 4.91 |
| Charles Nagy | Canaries | 4.99 |
| John Cerutti* | Rockets | 5.05 |
| Joe Slusarski | Rough Riders | 5.12 |
| Jose Mesa | Lemurs | 5.32 |
| Oil Can Boyd | Gnomes | 5.79 |
| Brian Barnes* | Millers | 5.92 |
| Roy Smith | Metropolitans | 6.06 |
| Rich DeLucia | Pachyderms | 6.35 |