| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 3/31/1961 | ASB | McAuliffe | Acquired via trade | EKL | | After |
| 3/31/1961 | ASB | Musial | Traded away | EKL | | After |
| 3/31/1961 | ASB | Osborne | Traded away | LOU | | After |
| 3/31/1961 | ASB | Regan | Acquired via trade | LOU | | After |
| 3/31/1961 | ASB | Worthington1963 | Traded away | EKL | | After |
| 3/31/1961 | BBC | Anderson,C | Acquired via trade | JOL | | After |
| 3/31/1961 | BBC | Arroyo | Traded away | JOL | | After |
| 3/31/1961 | BBC | Busby | Traded away | FRA | | After |
| 3/31/1961 | BBC | Carreon | Traded away | EKL | | After |
| 3/31/1961 | BBC | Ditmar,A | Acquired via trade | JOL | | After |
| 3/31/1961 | BBC | Freese,Ge | Acquired via trade | FRA | | After |
| 3/31/1961 | BBC | Golden | Acquired via trade | JOL | | After |
| 3/31/1961 | BBC | Hacker | Traded away | FRA | | After |
| 3/31/1961 | BBC | Koplitz | Traded away | JOL | | After |
| 3/31/1961 | BBC | Larsen,D | Traded away | JOL | | After |
| 3/31/1961 | BBC | Luplow | Acquired via trade | JOL | | After |
| 3/31/1961 | BBC | Mahoney | Traded away | JOL | | After |
| 3/31/1961 | BBC | Malzone | Traded away | FRA | | After |
| 3/31/1961 | BBC | Maxwell | Acquired via trade | FRA | | After |
| 3/31/1961 | BBC | Post | Traded away | FRA | | After |
| 3/31/1961 | BBC | Ramos | Acquired via trade | JOL | | After |
| 3/31/1961 | BBC | Roarke | Acquired via trade | JOL | | After |
| 3/31/1961 | BBC | Saverine 1962 | Acquired via trade | JOL | | After |
| 3/31/1961 | BBC | Stafford | Traded away | JOL | | After |
| 3/31/1961 | BBC | Throneberry,M | Traded away | JOL | | After |
| 3/31/1961 | BBC | Throneberry,M | Acquired via trade | FRA | | After |
| 3/31/1961 | BBC | Will | Acquired via trade | FRA | | After |
| 3/31/1961 | EKL | Carreon | Acquired via trade | BBC | | After |
| 3/31/1961 | EKL | Duren,R | Acquired via trade | JOL | | After |
| 3/31/1961 | EKL | Landrum | Traded away | JOL | | After |
| 3/31/1961 | EKL | McAuliffe | Traded away | ASB | | After |
| 3/31/1961 | EKL | Musial | Acquired via trade | ASB | | After |
| 3/31/1961 | EKL | Ridzik 1963 | Acquired via trade | NEW | | After |
| 3/31/1961 | EKL | Roarke | Traded away | JOL | | After |
| 3/31/1961 | EKL | Sullivan,H | Traded away | NEW | | After |
| 3/31/1961 | EKL | Worthington1963 | Acquired via trade | ASB | | After |
| 3/31/1961 | EKL | Zimmerman | Traded away | MAS | | After |
| 3/31/1961 | FRA | Busby | Acquired via trade | BBC | | After |
| 3/31/1961 | FRA | Dillard | Traded away | LOU | | After |
| 3/31/1961 | FRA | Freese,Ge | Traded away | BBC | | After |
| 3/31/1961 | FRA | Hacker | Acquired via trade | BBC | | After |
| 3/31/1961 | FRA | Kirkland | Acquired via trade | LOU | | After |
| 3/31/1961 | FRA | Malzone | Acquired via trade | BBC | | After |
| 3/31/1961 | FRA | Maxwell | Traded away | BBC | | After |
| 3/31/1961 | FRA | Post | Acquired via trade | BBC | | After |
| 3/31/1961 | FRA | Throneberry,M | Traded away | BBC | | After |
| 3/31/1961 | FRA | Will | Traded away | BBC | | After |
| 3/31/1961 | JOL | Anderson,C | Traded away | BBC | | After |
| 3/31/1961 | JOL | Arroyo | Acquired via trade | BBC | | After |
| 3/31/1961 | JOL | Ditmar,A | Traded away | BBC | | After |
| 3/31/1961 | JOL | Duren,R | Traded away | EKL | | After |
| 3/31/1961 | JOL | Golden | Traded away | BBC | | After |
| 3/31/1961 | JOL | Koplitz | Acquired via trade | BBC | | After |
| 3/31/1961 | JOL | Landrum | Acquired via trade | EKL | | After |
| 3/31/1961 | JOL | Larsen,D | Acquired via trade | BBC | | After |
| 3/31/1961 | JOL | Luplow | Traded away | BBC | | After |
| 3/31/1961 | JOL | Mahoney | Acquired via trade | BBC | | After |
| 3/31/1961 | JOL | Ramos | Traded away | BBC | | After |
| 3/31/1961 | JOL | Roarke | Traded away | BBC | | After |
| 3/31/1961 | JOL | Roarke | Acquired via trade | EKL | | After |
| 3/31/1961 | JOL | Saverine 1962 | Traded away | BBC | | After |
| 3/31/1961 | JOL | Smith,C | Traded away | NEW | | After |
| 3/31/1961 | JOL | Stafford | Acquired via trade | BBC | | After |
| 3/31/1961 | JOL | Throneberry,M | Acquired via trade | BBC | | After |
| 3/31/1961 | LOU | Amaro | Traded away | NBA | | After |
| 3/31/1961 | LOU | Christopher | Acquired via trade | NBA | | After |
| 3/31/1961 | LOU | Cisco | Traded away | MAS | | After |
| 3/31/1961 | LOU | Dillard | Acquired via trade | FRA | | After |
| 3/31/1961 | LOU | Ferrarese | Acquired via trade | MAS | | After |
| 3/31/1961 | LOU | Gladding | Acquired via trade | MAS | | After |
| 3/31/1961 | LOU | Gotay | Traded away | NBA | | After |
| 3/31/1961 | LOU | Hubbs | Acquired via trade | RIV | | After |
| 3/31/1961 | LOU | Kirkland | Traded away | FRA | | After |
| 3/31/1961 | LOU | McCormick | Traded away | RIV | | After |
| 3/31/1961 | LOU | Osborne | Acquired via trade | ASB | | After |
| 3/31/1961 | LOU | Regan | Traded away | ASB | | After |
| 3/31/1961 | LOU | Reniff | Acquired via trade | RIV | | After |
| 3/31/1961 | LOU | Sheldon | Acquired via trade | RIV | | After |
| 3/31/1961 | LOU | Stallard | Traded away | MAS | | After |
| 3/31/1961 | LOU | Wine 1962 | Acquired via trade | NBA | | After |
| 3/31/1961 | MAS | Cisco | Acquired via trade | LOU | | After |
| 3/31/1961 | MAS | Ferrarese | Traded away | LOU | | After |
| 3/31/1961 | MAS | Gladding | Traded away | LOU | | After |
| 3/31/1961 | MAS | Stallard | Acquired via trade | LOU | | After |
| 3/31/1961 | MAS | Zimmerman | Acquired via trade | EKL | | After |
| 3/31/1961 | NBA | Amaro | Acquired via trade | LOU | | After |
| 3/31/1961 | NBA | Christopher | Traded away | LOU | | After |
| 3/31/1961 | NBA | Gotay | Acquired via trade | LOU | | After |
| 3/31/1961 | NBA | Wine 1962 | Traded away | LOU | | After |
| 3/31/1961 | NEW | Daley,P | Acquired via trade | NYM | | After |
| 3/31/1961 | NEW | Garver | Acquired via trade | NYM | | After |
| 3/31/1961 | NEW | Ridzik 1963 | Traded away | EKL | | After |
| 3/31/1961 | NEW | Romano | Traded away | NYM | | After |
| 3/31/1961 | NEW | Smith,C | Acquired via trade | JOL | | After |
| 3/31/1961 | NEW | Sullivan,H | Acquired via trade | EKL | | After |
| 3/31/1961 | NYM | Averill | Acquired via trade | RAL | | After |
| 3/31/1961 | NYM | Daley,P | Traded away | NEW | | After |
| 3/31/1961 | NYM | Garver | Traded away | NEW | | After |
| 3/31/1961 | NYM | Hoeft | Acquired via trade | RAL | | After |
| 3/31/1961 | NYM | Hunt,K | Traded away | RAL | | After |
| 3/31/1961 | NYM | Jay | Acquired via trade | RAL | | After |
| 3/31/1961 | NYM | Romano | Acquired via trade | NEW | | After |
| 3/31/1961 | RAL | Averill | Traded away | NYM | | After |
| 3/31/1961 | RAL | Hoeft | Traded away | NYM | | After |
| 3/31/1961 | RAL | Hunt,K | Acquired via trade | NYM | | After |
| 3/31/1961 | RAL | Jay | Traded away | NYM | | After |
| 3/31/1961 | RIV | Hubbs | Traded away | LOU | | After |
| 3/31/1961 | RIV | McCormick | Acquired via trade | LOU | | After |
| 3/31/1961 | RIV | Reniff | Traded away | LOU | | After |
| 3/31/1961 | RIV | Sheldon | Traded away | LOU | | After |
| 4/7/1961 | BBC | Anderson,C | Promoted to active roster | | | Before |
| 4/7/1961 | BBC | Bailey,E | Promoted to active roster | | | Before |
| 4/7/1961 | BBC | Crandall | Promoted to active roster | | | Before |
| 4/7/1961 | BBC | de la Hoz | Promoted to active roster | | | Before |
| 4/7/1961 | BBC | Edwards | Demoted to reserve roster | | | Before |
| 4/7/1961 | BBC | Maxwell | Demoted to reserve roster | | | Before |
| 4/7/1961 | BBC | Roarke | Promoted to active roster | | | Before |
| 4/7/1961 | BBC | Satriano | Demoted to reserve roster | | | Before |
| 4/7/1961 | BBC | Thacker | Demoted to reserve roster | | | Before |
| 4/7/1961 | BBC | Will | Demoted to reserve roster | | | Before |
| 4/8/1961 | ASB | Bertell | Demoted to reserve roster | | | Before |
| 4/8/1961 | ASB | Burgess | Demoted to reserve roster | | | Before |
| 4/8/1961 | ASB | Freehan | Promoted to active roster | | | Before |
| 4/8/1961 | ASB | Leppert | Promoted to active roster | | | Before |
| 4/8/1961 | ASB | Schoendienst | Promoted to active roster | | | Before |
| 4/8/1961 | ASB | Veal | Demoted to reserve roster | | | Before |
| 4/8/1961 | FRA | Bright | Promoted to active roster | | | Before |
| 4/8/1961 | FRA | Orsino | Demoted to reserve roster | | | Before |
| 4/8/1961 | FRA | Raymond | Promoted to active roster | | | Before |
| 4/8/1961 | FRA | Rodgers,A | Demoted to reserve roster | | | Before |
| 4/8/1961 | FRA | Spring | Demoted to reserve roster | | | Before |
| 4/8/1961 | FRA | White,S | Promoted to active roster | | | Before |
| 4/8/1961 | MAS | Law | Demoted to reserve roster | | | Before |
| 4/8/1961 | MAS | Wickersham | Promoted to active roster | | | Before |
| 4/8/1961 | NEW | Brown,H | Demoted to reserve roster | | | Before |
| 4/8/1961 | NEW | Brown,H | Promoted to active roster | | | Before |
| 4/8/1961 | NEW | Cicotte | Demoted to reserve roster | | | Before |
| 4/8/1961 | NEW | Cicotte | Promoted to active roster | | | Before |
| 4/8/1961 | NEW | Haddix | Demoted to reserve roster | | | Before |
| 4/8/1961 | NEW | Haddix | Promoted to active roster | | | Before |
| 4/8/1961 | NEW | Roberts | Demoted to reserve roster | | | Before |
| 4/8/1961 | NEW | Roberts | Promoted to active roster | | | Before |
| 4/8/1961 | TOL | Aspromonte,K | Promoted to active roster | | | Before |
| 4/8/1961 | TOL | Schaffernoth,J | Promoted to active roster | | | Before |
| 4/8/1961 | TOL | Taylor,T | Demoted to reserve roster | | | Before |
| 4/8/1961 | TOL | Wynn | Demoted to reserve roster | | | Before |
| 4/14/1961 | ASB | Bertell | Promoted to active roster | | | Before |
| 4/14/1961 | ASB | Burgess | Promoted to active roster | | | Before |
| 4/14/1961 | ASB | Dobbek | Demoted to reserve roster | | | Before |
| 4/14/1961 | ASB | Freehan | Demoted to reserve roster | | | Before |
| 4/14/1961 | ASB | Leppert | Demoted to reserve roster | | | Before |
| 4/14/1961 | ASB | Veal | Promoted to active roster | | | Before |
| 4/14/1961 | BBC | Crandall | Demoted to reserve roster | | | Before |
| 4/14/1961 | BBC | Will | Promoted to active roster | | | Before |
| 4/14/1961 | RAL | Brunet | Demoted to reserve roster | | | Before |
| 4/14/1961 | RAL | Brunet | Promoted to active roster | | | Before |
| 4/14/1961 | RAL | Peters | Demoted to reserve roster | | | Before |
| 4/14/1961 | RAL | Wyatt | Promoted to active roster | | | Before |
| 4/16/1961 | EKL | Drabowsky | Promoted to active roster | | | Before |
| 4/16/1961 | EKL | Duren,R | Demoted to reserve roster | | | Before |
| 4/16/1961 | EKL | Fisher,E | Promoted to active roster | | | Before |
| 4/16/1961 | EKL | Green,D | Demoted to reserve roster | | | Before |
| 4/16/1961 | EKL | Nuxhall | Demoted to reserve roster | | | Before |
| 4/16/1961 | EKL | Oliver | Demoted to reserve roster | | | Before |
| 4/16/1961 | EKL | Warwick,C | Promoted to active roster | | | Before |
| 4/16/1961 | EKL | Woodeshick,H | Promoted to active roster | | | Before |
| 4/16/1961 | FRA | Busby | Promoted to active roster | | | Before |
| 4/16/1961 | FRA | Hacker | Demoted to reserve roster | | | Before |
| 4/16/1961 | FRA | Heist | Demoted to reserve roster | | | Before |
| 4/16/1961 | FRA | Malkmus | Demoted to reserve roster | | | Before |
| 4/16/1961 | FRA | Orsino | Promoted to active roster | | | Before |
| 4/16/1961 | FRA | Rodgers,A | Promoted to active roster | | | Before |
| 4/16/1961 | FRA | Spring | Promoted to active roster | | | Before |
| 4/16/1961 | FRA | White,S | Demoted to reserve roster | | | Before |
| 4/18/1961 | MAS | Law | Promoted to active roster | | | Before |
| 4/18/1961 | MAS | Nichols | Demoted to reserve roster | | | Before |
| 4/22/1961 | FRA | Bond | Promoted to active roster | | | Before |
| 4/22/1961 | FRA | Bright | Demoted to reserve roster | | | Before |
| 4/22/1961 | FRA | Busby | Demoted to reserve roster | | | Before |
| 4/22/1961 | FRA | Malkmus | Promoted to active roster | | | Before |
| 4/22/1961 | FRA | Orsino | Demoted to reserve roster | | | Before |
| 4/22/1961 | FRA | Rodgers,A | Demoted to reserve roster | | | Before |
| 4/22/1961 | FRA | Rodgers,A | Promoted to active roster | | | Before |
| 4/22/1961 | FRA | White,S | Promoted to active roster | | | Before |
| 4/22/1961 | MAS | Law | Demoted to reserve roster | | | Before |
| 4/22/1961 | MAS | Nichols | Promoted to active roster | | | Before |
| 4/23/1961 | BBC | Bailey,E | Demoted to reserve roster | | | Before |
| 4/23/1961 | BBC | Bailey,E | Promoted to active roster | | | Before |
| 4/23/1961 | BBC | Bailey,E | Demoted to reserve roster | | | Before |
| 4/23/1961 | BBC | Bailey,E | Promoted to active roster | | | Before |
| 4/23/1961 | BBC | Bell,Gu | Demoted to reserve roster | | | Before |
| 4/23/1961 | BBC | Crandall | Promoted to active roster | | | Before |
| 4/23/1961 | BBC | Edwards | Promoted to active roster | | | Before |
| 4/23/1961 | BBC | Harkness | Demoted to reserve roster | | | Before |
| 4/23/1961 | BBC | Harkness | Promoted to active roster | | | Before |
| 4/23/1961 | BBC | Maxwell | Promoted to active roster | | | Before |
| 4/23/1961 | BBC | Roarke | Demoted to reserve roster | | | Before |
| 4/23/1961 | BBC | Zipfel | Demoted to reserve roster | | | Before |
| 4/23/1961 | EKL | Bruce | Promoted to active roster | | | Before |
| 4/23/1961 | EKL | Drabowsky | Demoted to reserve roster | | | Before |
| 4/23/1961 | EKL | Duren,R | Promoted to active roster | | | Before |
| 4/23/1961 | EKL | Fisher,E | Demoted to reserve roster | | | Before |
| 4/23/1961 | EKL | Green,D | Promoted to active roster | | | Before |
| 4/23/1961 | EKL | Larker | Demoted to reserve roster | | | Before |
| 4/23/1961 | EKL | Musial | Demoted to reserve roster | | | Before |
| 4/23/1961 | EKL | Nuxhall | Promoted to active roster | | | Before |
| 4/23/1961 | JOL | Buzhardt | Promoted to active roster | | | Before |
| 4/23/1961 | JOL | Schwall | Demoted to reserve roster | | | Before |
| 4/23/1961 | RAL | Fregosi | Promoted to active roster | | | Before |
| 4/23/1961 | RAL | Hansen | Demoted to reserve roster | | | Before |
| 4/28/1961 | BBC | Golden | Promoted to active roster | | | Before |
| 4/28/1961 | BBC | Simmons | Demoted to reserve roster | | | Before |
| 4/29/1961 | MAS | Lopez | Promoted to active roster | | | Before |
| 4/29/1961 | MAS | Wickersham | Demoted to reserve roster | | | Before |
| 5/1/1961 | BBC | Crandall | Demoted to reserve roster | | | Before |
| 5/1/1961 | BBC | Golden | Demoted to reserve roster | | | Before |
| 5/1/1961 | BBC | Roarke | Demoted to reserve roster | | | Before |
| 5/1/1961 | BBC | Roarke | Promoted to active roster | | | Before |
| 5/1/1961 | BBC | Simmons | Promoted to active roster | | | Before |
| 5/1/1961 | BBC | Thacker | Demoted to reserve roster | | | Before |
| 5/1/1961 | BBC | Thacker | Promoted to active roster | | | Before |
| 5/1/1961 | BBC | Zipfel | Promoted to active roster | | | Before |
| 5/1/1961 | EKL | Larker | Promoted to active roster | | | Before |
| 5/1/1961 | EKL | Mincher | Demoted to reserve roster | | | Before |
| 5/1/1961 | EKL | Musial | Promoted to active roster | | | Before |
| 5/1/1961 | EKL | Tasby | Demoted to reserve roster | | | Before |
| 5/1/1961 | FRA | Hacker | Promoted to active roster | | | Before |
| 5/1/1961 | FRA | Raymond | Demoted to reserve roster | | | Before |
| 5/1/1961 | RAL | Fregosi | Demoted to reserve roster | | | Before |
| 5/1/1961 | RAL | Hansen | Promoted to active roster | | | Before |
| 5/8/1961 | JOL | McClain | Demoted to reserve roster | | | Before |
| 5/8/1961 | JOL | Schwall | Promoted to active roster | | | Before |
| 5/8/1961 | MOU | James,J | Promoted to active roster | | | Before |
| 5/8/1961 | MOU | McDevitt,D | Demoted to reserve roster | | | Before |
| 5/8/1961 | RIV | Ashburn | Promoted to active roster | | | Before |
| 5/8/1961 | RIV | Hardy | Demoted to reserve roster | | | Before |
| 5/8/1961 | RIV | Johnson,De | Promoted to active roster | | | Before |
| 5/8/1961 | RIV | Leek | Demoted to reserve roster | | | Before |
| 5/9/1961 | ASB | Olivo | Promoted to active roster | | | Before |
| 5/9/1961 | ASB | Staley,G | Demoted to reserve roster | | | Before |
| 5/9/1961 | FRA | Bilko | Demoted to reserve roster | | | Before |
| 5/9/1961 | FRA | Bond | Demoted to reserve roster | | | Before |
| 5/9/1961 | FRA | Bright | Promoted to active roster | | | Before |
| 5/9/1961 | FRA | Heist | Promoted to active roster | | | Before |
| 5/9/1961 | FRA | Malkmus | Demoted to reserve roster | | | Before |
| 5/9/1961 | FRA | Orsino | Promoted to active roster | | | Before |
| 5/9/1961 | MAS | Law | Promoted to active roster | | | Before |
| 5/9/1961 | MAS | Posada | Demoted to reserve roster | | | Before |
| 5/9/1961 | MAS | Sadowski,E | Demoted to reserve roster | | | Before |
| 5/9/1961 | MAS | Taussig | Promoted to active roster | | | Before |
| 5/15/1961 | ASB | Leppert | Promoted to active roster | | | Before |
| 5/15/1961 | ASB | Olivo | Demoted to reserve roster | | | Before |
| 5/15/1961 | ASB | Turley | Promoted to active roster | | | Before |
| 5/15/1961 | ASB | Veal | Demoted to reserve roster | | | Before |
| 5/15/1961 | MAS | Stallard | Demoted to reserve roster | | | Before |
| 5/15/1961 | MAS | Wickersham | Promoted to active roster | | | Before |
| 5/15/1961 | MOU | Landrith | Promoted to active roster | | | Before |
| 5/15/1961 | MOU | Naragon | Demoted to reserve roster | | | Before |
| 5/15/1961 | NEW | Cicotte | Demoted to reserve roster | | | Before |
| 5/15/1961 | NEW | Foytack | Promoted to active roster | | | Before |
| 5/15/1961 | NEW | Haddix | Promoted to active roster | | | Before |
| 5/15/1961 | NEW | Roberts | Demoted to reserve roster | | | Before |
| 5/16/1961 | EKL | Bruce | Demoted to reserve roster | | | Before |
| 5/16/1961 | EKL | Drabowsky | Promoted to active roster | | | Before |
| 5/16/1961 | EKL | Larker | Demoted to reserve roster | | | Before |
| 5/16/1961 | EKL | Mincher | Promoted to active roster | | | Before |
| 5/16/1961 | EKL | Musial | Demoted to reserve roster | | | Before |
| 5/16/1961 | EKL | Tasby | Promoted to active roster | | | Before |
| 5/16/1961 | FRA | Bilko | Promoted to active roster | | | Before |
| 5/16/1961 | FRA | Busby | Promoted to active roster | | | Before |
| 5/16/1961 | FRA | Camilli | Promoted to active roster | | | Before |
| 5/16/1961 | FRA | Morton | Demoted to reserve roster | | | Before |
| 5/16/1961 | FRA | Orsino | Demoted to reserve roster | | | Before |
| 5/16/1961 | FRA | White,S | Demoted to reserve roster | | | Before |
| 5/16/1961 | JOL | Daley,B | Demoted to reserve roster | | | Before |
| 5/16/1961 | JOL | McClain | Promoted to active roster | | | Before |
| 5/16/1961 | LOU | Johnson,L | Demoted to reserve roster | | | Before |
| 5/16/1961 | LOU | Krausse | Promoted to active roster | | | Before |
| 5/16/1961 | LOU | Osborne | Promoted to active roster | | | Before |
| 5/16/1961 | LOU | Reniff | Demoted to reserve roster | | | Before |
| 5/16/1961 | NBA | Alou,M | Demoted to reserve roster | | | Before |
| 5/16/1961 | NBA | Becquer,J | Promoted to active roster | | | Before |
| 5/16/1961 | NBA | Brewer,T | Demoted to reserve roster | | | Before |
| 5/16/1961 | NBA | Clinton | Promoted to active roster | | | Before |
| 5/23/1961 | ASB | Bertell | Demoted to reserve roster | | | Before |
| 5/23/1961 | ASB | Veal | Promoted to active roster | | | Before |
| 5/23/1961 | EKL | Drabowsky | Demoted to reserve roster | | | Before |
| 5/23/1961 | EKL | Fisher,E | Promoted to active roster | | | Before |
| 5/23/1961 | EKL | Larker | Promoted to active roster | | | Before |
| 5/23/1961 | EKL | Mincher | Demoted to reserve roster | | | Before |
| 5/23/1961 | EKL | Musial | Promoted to active roster | | | Before |
| 5/23/1961 | EKL | Warwick,C | Demoted to reserve roster | | | Before |
| 5/23/1961 | JOL | Daley,B | Promoted to active roster | | | Before |
| 5/23/1961 | JOL | Schwall | Demoted to reserve roster | | | Before |
| 5/23/1961 | MAS | Law | Demoted to reserve roster | | | Before |
| 5/23/1961 | MAS | Stallard | Promoted to active roster | | | Before |
| 5/24/1961 | BBC | Bailey,E | Demoted to reserve roster | | | Before |
| 5/24/1961 | BBC | Bell,Gu | Promoted to active roster | | | Before |
| 5/24/1961 | BBC | Ditmar,A | Demoted to reserve roster | | | Before |
| 5/24/1961 | BBC | Harkness | Promoted to active roster | | | Before |
| 5/24/1961 | BBC | Satriano | Promoted to active roster | | | Before |
| 5/24/1961 | BBC | Thacker | Promoted to active roster | | | Before |
| 5/24/1961 | BBC | Will | Demoted to reserve roster | | | Before |
| 5/24/1961 | BBC | Zipfel | Demoted to reserve roster | | | Before |
| 5/24/1961 | NBA | Aspromonte,B | Promoted to active roster | | | Before |
| 5/24/1961 | NBA | Bressoud | Demoted to reserve roster | | | Before |
| 5/24/1961 | NBA | Mantilla | Promoted to active roster | | | Before |
| 5/24/1961 | NBA | Snyder,R | Demoted to reserve roster | | | Before |
| 5/24/1961 | RAL | Wyatt | Demoted to reserve roster | | | Before |
| 5/24/1961 | RIV | Howard,F | Demoted to reserve roster | | | Before |
| 5/24/1961 | RIV | Johnson,De | Promoted to active roster | | | Before |
| 5/30/1961 | MAS | Lopez | Demoted to reserve roster | | | Before |
| 5/30/1961 | MAS | Posada | Promoted to active roster | | | Before |
| 5/30/1961 | MAS | Sadowski,E | Promoted to active roster | | | Before |
| 5/30/1961 | MAS | Zimmerman | Demoted to reserve roster | | | Before |
| 5/30/1961 | NBA | Aspromonte,B | Demoted to reserve roster | | | Before |
| 5/30/1961 | NBA | Becquer,J | Demoted to reserve roster | | | Before |
| 5/30/1961 | NBA | Bressoud | Promoted to active roster | | | Before |
| 5/30/1961 | NBA | Snyder,R | Promoted to active roster | | | Before |
| 6/3/1961 | ASB | Burgess | Demoted to reserve roster | | | Before |
| 6/3/1961 | ASB | Casale,J | Promoted to active roster | | | Before |
| 6/3/1961 | ASB | Courtney,C | Promoted to active roster | | | Before |
| 6/3/1961 | ASB | Delock | Demoted to reserve roster | | | Before |
| 6/3/1961 | ASB | Dobbek | Promoted to active roster | | | Before |
| 6/3/1961 | ASB | Klippstein | Demoted to reserve roster | | | Before |
| 6/3/1961 | ASB | Lemon | Demoted to reserve roster | | | Before |
| 6/3/1961 | ASB | Staley,G | Promoted to active roster | | | Before |
| 6/3/1961 | BBC | Bailey,E | Promoted to active roster | | | Before |
| 6/3/1961 | BBC | Crandall | Promoted to active roster | | | Before |
| 6/3/1961 | BBC | Harkness | Demoted to reserve roster | | | Before |
| 6/3/1961 | BBC | Thacker | Demoted to reserve roster | | | Before |
| 6/3/1961 | FRA | Busby | Demoted to reserve roster | | | Before |
| 6/3/1961 | FRA | Camilli | Demoted to reserve roster | | | Before |
| 6/3/1961 | FRA | Morton | Promoted to active roster | | | Before |
| 6/3/1961 | FRA | Orsino | Promoted to active roster | | | Before |
| 6/3/1961 | FRA | Piche | Promoted to active roster | | | Before |
| 6/3/1961 | FRA | Spring | Demoted to reserve roster | | | Before |
| 6/3/1961 | JOL | McClain | Demoted to reserve roster | | | Before |
| 6/3/1961 | JOL | Schwall | Promoted to active roster | | | Before |
| 6/3/1961 | TOL | Aspromonte,K | Demoted to reserve roster | | | Before |
| 6/3/1961 | TOL | Owens | Demoted to reserve roster | | | Before |
| 6/3/1961 | TOL | Schaffernoth,J | Demoted to reserve roster | | | Before |
| 6/3/1961 | TOL | Smith,B | Demoted to reserve roster | | | Before |
| 6/3/1961 | TOL | Taylor,T | Promoted to active roster | | | Before |
| 6/3/1961 | TOL | Wynn | Promoted to active roster | | | Before |
| 6/9/1961 | ASB | Bertell | Promoted to active roster | | | Before |
| 6/9/1961 | ASB | Burgess | Promoted to active roster | | | Before |
| 6/9/1961 | ASB | Courtney,C | Demoted to reserve roster | | | Before |
| 6/9/1961 | ASB | Leppert | Demoted to reserve roster | | | Before |
| 6/9/1961 | BBC | Bell,Gu | Demoted to reserve roster | | | Before |
| 6/9/1961 | BBC | Bell,Gu | Promoted to active roster | | | Before |
| 6/9/1961 | BBC | Crandall | Demoted to reserve roster | | | Before |
| 6/9/1961 | BBC | Ditmar,A | Promoted to active roster | | | Before |
| 6/9/1961 | BBC | Edwards | Demoted to reserve roster | | | Before |
| 6/9/1961 | BBC | Edwards | Promoted to active roster | | | Before |
| 6/9/1961 | BBC | Hiller | Demoted to reserve roster | | | Before |
| 6/9/1961 | BBC | Roarke | Promoted to active roster | | | Before |
| 6/9/1961 | BBC | Satriano | Demoted to reserve roster | | | Before |
| 6/9/1961 | BBC | Thacker | Demoted to reserve roster | | | Before |
| 6/9/1961 | BBC | Thacker | Promoted to active roster | | | Before |
| 6/9/1961 | BBC | Will | Promoted to active roster | | | Before |
| 6/9/1961 | BBC | Zipfel | Demoted to reserve roster | | | Before |
| 6/9/1961 | BBC | Zipfel | Promoted to active roster | | | Before |
| 6/9/1961 | BBC | Zipfel | Demoted to reserve roster | | | Before |
| 6/9/1961 | BBC | Zipfel | Promoted to active roster | | | Before |
| 6/9/1961 | MOU | Koppe,J | Promoted to active roster | | | Before |
| 6/9/1961 | MOU | Landrith | Demoted to reserve roster | | | Before |
| 6/10/1961 | EKL | Baumann | Demoted to reserve roster | | | Before |
| 6/10/1961 | EKL | Bruce | Promoted to active roster | | | Before |
| 6/10/1961 | EKL | Drabowsky | Promoted to active roster | | | Before |
| 6/10/1961 | EKL | Fisher,E | Demoted to reserve roster | | | Before |
| 6/10/1961 | EKL | Larker | Demoted to reserve roster | | | Before |
| 6/10/1961 | EKL | Mincher | Promoted to active roster | | | Before |
| 6/10/1961 | EKL | Musial | Demoted to reserve roster | | | Before |
| 6/10/1961 | EKL | Warwick,C | Promoted to active roster | | | Before |
| 6/10/1961 | FRA | Bond | Promoted to active roster | | | Before |
| 6/10/1961 | FRA | Bright | Demoted to reserve roster | | | Before |
| 6/10/1961 | FRA | Hacker | Demoted to reserve roster | | | Before |
| 6/10/1961 | FRA | Malkmus | Promoted to active roster | | | Before |
| 6/10/1961 | FRA | Morton | Demoted to reserve roster | | | Before |
| 6/10/1961 | FRA | Orsino | Demoted to reserve roster | | | Before |
| 6/10/1961 | FRA | Spring | Promoted to active roster | | | Before |
| 6/10/1961 | FRA | White,S | Promoted to active roster | | | Before |
| 6/10/1961 | JOL | Daley,B | Demoted to reserve roster | | | Before |
| 6/10/1961 | JOL | McClain | Promoted to active roster | | | Before |
| 6/10/1961 | NBA | Aspromonte,B | Promoted to active roster | | | Before |
| 6/10/1961 | NBA | Hodges | Demoted to reserve roster | | | Before |
| 6/10/1961 | RIV | Ashburn | Promoted to active roster | | | Before |
| 6/10/1961 | RIV | Hardy | Demoted to reserve roster | | | Before |
| 6/16/1961 | EKL | Larker | Promoted to active roster | | | Before |
| 6/16/1961 | EKL | Mincher | Demoted to reserve roster | | | Before |
| 6/16/1961 | EKL | Musial | Promoted to active roster | | | Before |
| 6/16/1961 | EKL | Warwick,C | Demoted to reserve roster | | | Before |
| 6/16/1961 | JOL | Larsen,D | Promoted to active roster | | | Before |
| 6/16/1961 | JOL | Stafford | Demoted to reserve roster | | | Before |
| 6/16/1961 | LOU | Clinton | Acquired via trade | NBA | | After |
| 6/16/1961 | LOU | Francis | Traded away | NBA | | After |
| 6/16/1961 | MAS | Arrigo | Promoted to active roster | | | Before |
| 6/16/1961 | MAS | Haller | Promoted to active roster | | | Before |
| 6/16/1961 | MAS | Law | Demoted to reserve roster | | | Before |
| 6/16/1961 | MAS | Law | Promoted to active roster | | | Before |
| 6/16/1961 | MAS | Lopez | Promoted to active roster | | | Before |
| 6/16/1961 | MAS | Posada | Demoted to reserve roster | | | Before |
| 6/16/1961 | MAS | Sadowski,E | Demoted to reserve roster | | | Before |
| 6/16/1961 | MAS | Smith,HR | Demoted to reserve roster | | | Before |
| 6/16/1961 | MAS | Wickersham | Demoted to reserve roster | | | Before |
| 6/16/1961 | MAS | Zimmerman | Promoted to active roster | | | Before |
| 6/16/1961 | MOU | Bolin | Demoted to reserve roster | | | Before |
| 6/16/1961 | MOU | Cunningham | Demoted to reserve roster | | | Before |
| 6/16/1961 | MOU | Dailey | Promoted to active roster | | | Before |
| 6/16/1961 | MOU | Sherry,N | Promoted to active roster | | | Before |
| 6/16/1961 | NBA | Clinton | Demoted to reserve roster | | | Before |
| 6/16/1961 | NBA | Clinton | Traded away | LOU | | After |
| 6/16/1961 | NBA | Francis | Acquired via trade | LOU | | After |
| 6/17/1961 | EKL | Drabowsky | Demoted to reserve roster | | | Before |
| 6/17/1961 | EKL | Oliver | Promoted to active roster | | | Before |
| 6/17/1961 | FRA | Bond | Demoted to reserve roster | | | Before |
| 6/17/1961 | FRA | Camilli | Promoted to active roster | | | Before |
| 6/17/1961 | FRA | Morton | Promoted to active roster | | | Before |
| 6/17/1961 | FRA | White,S | Demoted to reserve roster | | | Before |
| 6/17/1961 | NBA | Francis | Promoted to active roster | | | Before |
| 6/17/1961 | NBA | Hodges | Promoted to active roster | | | Before |
| 6/17/1961 | NBA | Runnels | Demoted to reserve roster | | | Before |
| 6/17/1961 | NEW | Fox,T | Promoted to active roster | | | Before |
| 6/17/1961 | NEW | Garver | Demoted to reserve roster | | | Before |
| 6/17/1961 | NEW | Moore | Demoted to reserve roster | | | Before |
| 6/23/1961 | EKL | Baumann | Promoted to active roster | | | Before |
| 6/23/1961 | EKL | Oliver | Demoted to reserve roster | | | Before |
| 6/23/1961 | EKL | Warwick,C | Promoted to active roster | | | Before |
| 6/23/1961 | EKL | Woodeshick,H | Demoted to reserve roster | | | Before |
| 6/23/1961 | MAS | Arrigo | Demoted to reserve roster | | | Before |
| 6/23/1961 | MAS | Cisco | Promoted to active roster | | | Before |
| 6/23/1961 | MAS | Haller | Demoted to reserve roster | | | Before |
| 6/23/1961 | MAS | Sadowski,E | Promoted to active roster | | | Before |
| 6/23/1961 | MAS | Smith,HR | Promoted to active roster | | | Before |
| 6/23/1961 | MAS | Zimmerman | Demoted to reserve roster | | | Before |
| 6/23/1961 | NBA | Alou,M | Promoted to active roster | | | Before |
| 6/23/1961 | NBA | Hodges | Demoted to reserve roster | | | Before |
| 6/23/1961 | NBA | Rivera,J | Demoted to reserve roster | | | Before |
| 6/23/1961 | NBA | Runnels | Promoted to active roster | | | Before |
| 6/23/1961 | NBA | Schofield | Promoted to active roster | | | Before |
| 6/23/1961 | NBA | Snyder,R | Demoted to reserve roster | | | Before |
| 6/23/1961 | NEW | Daley,P | Demoted to reserve roster | | | Before |
| 6/23/1961 | NEW | Kluszewski | Demoted to reserve roster | | | Before |
| 6/24/1961 | BBC | Cerv,B | Demoted to reserve roster | | | Before |
| 6/24/1961 | BBC | Golden | Demoted to reserve roster | | | Before |
| 6/24/1961 | BBC | Golden | Promoted to active roster | | | Before |
| 6/24/1961 | BBC | Hiller | Promoted to active roster | | | Before |
| 6/24/1961 | BBC | Roarke | Demoted to reserve roster | | | Before |
| 6/24/1961 | BBC | Satriano | Promoted to active roster | | | Before |
| 6/24/1961 | BBC | Thacker | Demoted to reserve roster | | | Before |
| 6/24/1961 | BBC | Thacker | Promoted to active roster | | | Before |
| 6/24/1961 | FRA | Bond | Promoted to active roster | | | Before |
| 6/24/1961 | FRA | Bright | Promoted to active roster | | | Before |
| 6/24/1961 | FRA | Camilli | Demoted to reserve roster | | | Before |
| 6/24/1961 | FRA | Hacker | Promoted to active roster | | | Before |
| 6/24/1961 | FRA | Malkmus | Demoted to reserve roster | | | Before |
| 6/24/1961 | FRA | Morton | Demoted to reserve roster | | | Before |
| 6/24/1961 | FRA | Orsino | Promoted to active roster | | | Before |
| 6/24/1961 | FRA | Piche | Demoted to reserve roster | | | Before |
| 6/24/1961 | NYM | Farrell,T | Demoted to reserve roster | | | Before |
| 6/24/1961 | NYM | McCarver | Promoted to active roster | | | Before |
| 6/24/1961 | RAL | Brunet | Promoted to active roster | | | Before |
| 6/24/1961 | RAL | Hook | Demoted to reserve roster | | | Before |
| 6/30/1961 | NYM | McCarver | Demoted to reserve roster | | | Before |
| 7/3/1961 | ASB | Delock | Promoted to active roster | | | Before |
| 7/3/1961 | ASB | Dobbek | Demoted to reserve roster | | | Before |
| 7/3/1961 | ASB | Klippstein | Promoted to active roster | | | Before |
| 7/3/1961 | ASB | Lemon | Promoted to active roster | | | Before |
| 7/3/1961 | ASB | Sturdivant,T | Demoted to reserve roster | | | Before |
| 7/3/1961 | ASB | Veal | Demoted to reserve roster | | | Before |
| 7/3/1961 | BBC | Bell,Gu | Demoted to reserve roster | | | Before |
| 7/3/1961 | BBC | Cerv,B | Promoted to active roster | | | Before |
| 7/3/1961 | BBC | Edwards | Demoted to reserve roster | | | Before |
| 7/3/1961 | BBC | Maxwell | Demoted to reserve roster | | | Before |
| 7/3/1961 | BBC | Maxwell | Promoted to active roster | | | Before |
| 7/3/1961 | BBC | Roarke | Promoted to active roster | | | Before |
| 7/3/1961 | BBC | Satriano | Demoted to reserve roster | | | Before |
| 7/3/1961 | BBC | Zipfel | Promoted to active roster | | | Before |
| 7/3/1961 | FRA | Bond | Demoted to reserve roster | | | Before |
| 7/3/1961 | FRA | Busby | Promoted to active roster | | | Before |
| 7/3/1961 | FRA | Orsino | Demoted to reserve roster | | | Before |
| 7/3/1961 | FRA | Roselli | Promoted to active roster | | | Before |
| 7/3/1961 | JOL | Daley,B | Promoted to active roster | | | Before |
| 7/3/1961 | JOL | Grba | Demoted to reserve roster | | | Before |
| 7/3/1961 | JOL | McClain | Demoted to reserve roster | | | Before |
| 7/3/1961 | JOL | Stafford | Promoted to active roster | | | Before |
| 7/3/1961 | MAS | Cisco | Demoted to reserve roster | | | Before |
| 7/3/1961 | MAS | Stallard | Demoted to reserve roster | | | Before |
| 7/3/1961 | MAS | Stallard | Promoted to active roster | | | Before |
| 7/3/1961 | MAS | Washburn | Demoted to reserve roster | | | Before |
| 7/3/1961 | MAS | Washburn | Promoted to active roster | | | Before |
| 7/3/1961 | MAS | Washburn | Promoted to active roster | | | Before |
| 7/3/1961 | NEW | Daley,P | Released | | | Before |
| 7/3/1961 | NEW | Garver | Released | | | Before |
| 7/3/1961 | NEW | Schroll | Signed | | | Before |
| 7/3/1961 | NEW | Schroll | Demoted to reserve roster | | | Before |
| 7/3/1961 | NEW | Thomas,V | Signed | | | Before |
| 7/3/1961 | NEW | Thomas,V | Demoted to reserve roster | | | Before |
| 7/9/1961 | BBC | Bell,Gu | Promoted to active roster | | | Before |
| 7/9/1961 | BBC | Zipfel | Demoted to reserve roster | | | Before |
| 7/9/1961 | JOL | Estrada | Demoted to reserve roster | | | Before |
| 7/9/1961 | JOL | McClain | Promoted to active roster | | | Before |
| 7/9/1961 | NEW | Daley,P | Released | | | Before |
| 7/9/1961 | NEW | Daley,P | Signed | | | Before |
| 7/9/1961 | NEW | Daley,P | Demoted to reserve roster | | | Before |
| 7/9/1961 | NEW | Garver | Released | | | Before |
| 7/9/1961 | NEW | Garver | Signed | | | Before |
| 7/9/1961 | NEW | Garver | Demoted to reserve roster | | | Before |
| 7/9/1961 | NEW | Schroll | Released | | | Before |
| 7/9/1961 | NEW | Schroll | Signed | | | Before |
| 7/9/1961 | NEW | Schroll | Demoted to reserve roster | | | Before |
| 7/9/1961 | NEW | Schroll | Promoted to active roster | | | Before |
| 7/9/1961 | NEW | Thomas,V | Released | | | Before |
| 7/9/1961 | NEW | Thomas,V | Signed | | | Before |
| 7/9/1961 | NEW | Thomas,V | Demoted to reserve roster | | | Before |
| 7/9/1961 | NEW | Thomas,V | Promoted to active roster | | | Before |
| 7/9/1961 | RAL | Cheney,T | Demoted to reserve roster | | | Before |
| 7/9/1961 | RAL | Moeller | Promoted to active roster | | | Before |
| 7/10/1961 | EKL | Drabowsky | Promoted to active roster | | | Before |
| 7/10/1961 | EKL | Duren,R | Demoted to reserve roster | | | Before |
| 7/10/1961 | EKL | Jackson,A | Promoted to active roster | | | Before |
| 7/10/1961 | EKL | Jackson,L | Demoted to reserve roster | | | Before |
| 7/10/1961 | EKL | Lollar | Demoted to reserve roster | | | Before |
| 7/10/1961 | EKL | Nuxhall | Demoted to reserve roster | | | Before |
| 7/10/1961 | EKL | Oliver | Promoted to active roster | | | Before |
| 7/10/1961 | EKL | Woodeshick,H | Promoted to active roster | | | Before |
| 7/10/1961 | FRA | Malkmus | Demoted to reserve roster | | | Before |
| 7/10/1961 | FRA | Malkmus | Promoted to active roster | | | Before |
| 7/10/1961 | FRA | Orsino | Promoted to active roster | | | Before |
| 7/10/1961 | FRA | Roselli | Demoted to reserve roster | | | Before |
| 7/10/1961 | FRA | White,S | Demoted to reserve roster | | | Before |
| 7/10/1961 | FRA | White,S | Promoted to active roster | | | Before |
| 7/10/1961 | NEW | Fox,T | Demoted to reserve roster | | | Before |
| 7/10/1961 | NEW | Nunn | Promoted to active roster | | | Before |
| 7/10/1961 | NEW | Philley | Promoted to active roster | | | Before |
| 7/11/1961 | MAS | Goodman | Demoted to reserve roster | | | Before |
| 7/11/1961 | MAS | Law | Promoted to active roster | | | Before |
| 7/16/1961 | MAS | Cisco | Promoted to active roster | | | Before |
| 7/16/1961 | MAS | Goodman | Promoted to active roster | | | Before |
| 7/16/1961 | MAS | Stallard | Demoted to reserve roster | | | Before |
| 7/16/1961 | MAS | Washburn | Demoted to reserve roster | | | Before |
| 7/16/1961 | MOU | Bolin | Promoted to active roster | | | Before |
| 7/16/1961 | MOU | Dailey | Demoted to reserve roster | | | Before |
| 7/16/1961 | MOU | Pignatano | Demoted to reserve roster | | | Before |
| 7/16/1961 | MOU | Retzer | Promoted to active roster | | | Before |
| 7/16/1961 | NBA | Alou,M | Demoted to reserve roster | | | Before |
| 7/16/1961 | NBA | Hodges | Promoted to active roster | | | Before |
| 7/16/1961 | NBA | Mantilla | Demoted to reserve roster | | | Before |
| 7/16/1961 | NBA | Snyder,R | Promoted to active roster | | | Before |
| 7/16/1961 | NEW | Aguirre | Promoted to active roster | | | Before |
| 7/16/1961 | NEW | Bridges,M | Demoted to reserve roster | | | Before |
| 7/16/1961 | NEW | Cicotte | Demoted to reserve roster | | | Before |
| 7/16/1961 | NEW | Foytack | Demoted to reserve roster | | | Before |
| 7/16/1961 | NEW | Foytack | Promoted to active roster | | | Before |
| 7/16/1961 | NEW | Haddix | Demoted to reserve roster | | | Before |
| 7/16/1961 | NEW | Moore | Promoted to active roster | | | Before |
| 7/16/1961 | NEW | Rodgers,B | Promoted to active roster | | | Before |
| 7/17/1961 | EKL | Baumann | Demoted to reserve roster | | | Before |
| 7/17/1961 | EKL | Duren,R | Promoted to active roster | | | Before |
| 7/17/1961 | EKL | Jackson,A | Demoted to reserve roster | | | Before |
| 7/17/1961 | EKL | Jackson,L | Promoted to active roster | | | Before |
| 7/17/1961 | EKL | Larker | Demoted to reserve roster | | | Before |
| 7/17/1961 | EKL | Lollar | Promoted to active roster | | | Before |
| 7/17/1961 | EKL | Mincher | Promoted to active roster | | | Before |
| 7/17/1961 | EKL | Oliver | Demoted to reserve roster | | | Before |
| 7/17/1961 | FRA | Orsino | Demoted to reserve roster | | | Before |
| 7/17/1961 | FRA | White,S | Promoted to active roster | | | Before |
| 7/17/1961 | NYM | Breeding | Promoted to active roster | | | Before |
| 7/17/1961 | NYM | Donovan | Demoted to reserve roster | | | Before |
| 7/17/1961 | RAL | King | Demoted to reserve roster | | | Before |
| 7/21/1961 | ASB | Delock | Demoted to reserve roster | | | Before |
| 7/21/1961 | ASB | Sturdivant,T | Promoted to active roster | | | Before |
| 7/21/1961 | EKL | Baumann | Promoted to active roster | | | Before |
| 7/21/1961 | EKL | Jackson,L | Demoted to reserve roster | | | Before |
| 7/21/1961 | EKL | Larker | Promoted to active roster | | | Before |
| 7/21/1961 | EKL | Mincher | Demoted to reserve roster | | | Before |
| 7/21/1961 | MAS | Haller | Promoted to active roster | | | Before |
| 7/21/1961 | MAS | Sadowski,E | Demoted to reserve roster | | | Before |
| 7/21/1961 | MAS | Smith,HR | Demoted to reserve roster | | | Before |
| 7/21/1961 | MAS | Zimmerman | Promoted to active roster | | | Before |
| 7/21/1961 | NBA | Bressoud | Demoted to reserve roster | | | Before |
| 7/21/1961 | NBA | Buchek | Promoted to active roster | | | Before |
| 7/21/1961 | NBA | Rivera,J | Promoted to active roster | | | Before |
| 7/21/1961 | NBA | Schofield | Demoted to reserve roster | | | Before |
| 7/24/1961 | BBC | Crandall | Promoted to active roster | | | Before |
| 7/24/1961 | BBC | Ditmar,A | Demoted to reserve roster | | | Before |
| 7/24/1961 | BBC | Golden | Promoted to active roster | | | Before |
| 7/24/1961 | BBC | Maxwell | Demoted to reserve roster | | | Before |
| 7/24/1961 | BBC | Roarke | Demoted to reserve roster | | | Before |
| 7/24/1961 | BBC | Satriano | Promoted to active roster | | | Before |
| 7/24/1961 | BBC | Temple | Demoted to reserve roster | | | Before |
| 7/24/1961 | BBC | Thacker | Promoted to active roster | | | Before |
| 7/24/1961 | BBC | Will | Demoted to reserve roster | | | Before |
| 7/24/1961 | BBC | Zipfel | Promoted to active roster | | | Before |
| 7/24/1961 | FRA | Orsino | Promoted to active roster | | | Before |
| 7/24/1961 | FRA | White,S | Demoted to reserve roster | | | Before |
| 7/24/1961 | JOL | Grba | Promoted to active roster | | | Before |
| 7/24/1961 | JOL | McClain | Demoted to reserve roster | | | Before |
| 7/24/1961 | MOU | Dailey | Demoted to reserve roster | | | Before |
| 7/24/1961 | MOU | McDevitt,D | Promoted to active roster | | | Before |
| 7/24/1961 | MOU | Pignatano | Demoted to reserve roster | | | Before |
| 7/24/1961 | MOU | Retzer | Promoted to active roster | | | Before |
| 7/24/1961 | NYM | Donovan | Promoted to active roster | | | Before |
| 7/24/1961 | NYM | Ford | Demoted to reserve roster | | | Before |
| 7/24/1961 | NYM | Heman,R | Promoted to active roster | | | Before |
| 7/24/1961 | NYM | Jay | Demoted to reserve roster | | | Before |
| 7/29/1961 | BBC | Anderson,C | Demoted to reserve roster | | | Before |
| 7/29/1961 | BBC | Crandall | Demoted to reserve roster | | | Before |
| 7/29/1961 | BBC | Ditmar,A | Promoted to active roster | | | Before |
| 7/29/1961 | BBC | Roarke | Promoted to active roster | | | Before |
| 7/29/1961 | BBC | Satriano | Demoted to reserve roster | | | Before |
| 7/29/1961 | BBC | Temple | Promoted to active roster | | | Before |
| 7/29/1961 | BBC | Thacker | Demoted to reserve roster | | | Before |
| 7/29/1961 | BBC | Will | Promoted to active roster | | | Before |
| 7/29/1961 | MAS | Haller | Demoted to reserve roster | | | Before |
| 7/29/1961 | MAS | Law | Demoted to reserve roster | | | Before |
| 7/29/1961 | MAS | Sadowski,E | Promoted to active roster | | | Before |
| 7/29/1961 | MAS | Smith,HR | Promoted to active roster | | | Before |
| 7/29/1961 | MAS | Stallard | Promoted to active roster | | | Before |
| 7/29/1961 | MAS | Zimmerman | Demoted to reserve roster | | | Before |
| 7/29/1961 | NYM | Burdette | Demoted to reserve roster | | | Before |
| 7/29/1961 | NYM | Donovan | Demoted to reserve roster | | | Before |
| 7/29/1961 | NYM | Farrell,T | Promoted to active roster | | | Before |
| 7/29/1961 | NYM | Ford | Promoted to active roster | | | Before |
| 8/3/1961 | ASB | Bertell | Demoted to reserve roster | | | Before |
| 8/3/1961 | ASB | Bertell | Promoted to active roster | | | Before |
| 8/3/1961 | ASB | Burgess | Demoted to reserve roster | | | Before |
| 8/3/1961 | ASB | Dobbek | Promoted to active roster | | | Before |
| 8/3/1961 | ASB | Gonzalez | Demoted to reserve roster | | | Before |
| 8/3/1961 | ASB | Leppert | Promoted to active roster | | | Before |
| 8/3/1961 | EKL | Drabowsky | Demoted to reserve roster | | | Before |
| 8/3/1961 | EKL | Jackson,L | Promoted to active roster | | | Before |
| 8/3/1961 | FRA | Orsino | Demoted to reserve roster | | | Before |
| 8/3/1961 | FRA | White,S | Promoted to active roster | | | Before |
| 8/3/1961 | RAL | Bauta | Promoted to active roster | | | Before |
| 8/3/1961 | RAL | Maloney | Demoted to reserve roster | | | Before |
| 8/3/1961 | RIV | Altman | Demoted to reserve roster | | | Before |
| 8/3/1961 | RIV | Hardy | Promoted to active roster | | | Before |
| 8/3/1961 | RIV | Hershberger | Promoted to active roster | | | Before |
| 8/3/1961 | RIV | Klaus | Promoted to active roster | | | Before |
| 8/3/1961 | RIV | Kubek | Demoted to reserve roster | | | Before |
| 8/3/1961 | RIV | Thomas,L | Demoted to reserve roster | | | Before |
| 8/3/1961 | TOL | Lau,C | Promoted to active roster | | | Before |
| 8/3/1961 | TOL | Taylor,S | Demoted to reserve roster | | | Before |
| 8/4/1961 | EKL | Hobbie | Demoted to reserve roster | | | Before |
| 8/4/1961 | EKL | Nuxhall | Promoted to active roster | | | Before |
| 8/8/1961 | ASB | Burgess | Promoted to active roster | | | Before |
| 8/8/1961 | ASB | Dobbek | Demoted to reserve roster | | | Before |
| 8/8/1961 | ASB | Gonzalez | Promoted to active roster | | | Before |
| 8/8/1961 | ASB | Leppert | Demoted to reserve roster | | | Before |
| 8/8/1961 | ASB | Perry | Demoted to reserve roster | | | Before |
| 8/8/1961 | ASB | Veal | Promoted to active roster | | | Before |
| 8/8/1961 | EKL | Bruce | Demoted to reserve roster | | | Before |
| 8/8/1961 | EKL | Drabowsky | Promoted to active roster | | | Before |
| 8/8/1961 | EKL | Hobbie | Promoted to active roster | | | Before |
| 8/8/1961 | EKL | Larker | Demoted to reserve roster | | | Before |
| 8/8/1961 | EKL | Mincher | Promoted to active roster | | | Before |
| 8/8/1961 | EKL | Woodeshick,H | Demoted to reserve roster | | | Before |
| 8/8/1961 | RIV | Altman | Promoted to active roster | | | Before |
| 8/8/1961 | RIV | Hershberger | Demoted to reserve roster | | | Before |
| 8/8/1961 | TOL | Cardenas | Demoted to reserve roster | | | Before |
| 8/8/1961 | TOL | Carey,A | Promoted to active roster | | | Before |
| 8/10/1961 | BBC | Cerv,B | Released | | | Before |
| 8/10/1961 | BBC | Edwards | Promoted to active roster | | | Before |
| 8/10/1961 | BBC | Garcia | Signed | | | Before |
| 8/10/1961 | BBC | Jones,Sh | Released | | | Before |
| 8/10/1961 | BBC | Klimchock | Signed | | | Before |
| 8/10/1961 | BBC | McDermott,M | Signed | | | Before |
| 8/10/1961 | BBC | Roarke | Released | | | Before |
| 8/10/1961 | BBC | Will | Demoted to reserve roster | | | Before |
| 8/10/1961 | FRA | Orsino | Promoted to active roster | | | Before |
| 8/10/1961 | FRA | White,S | Demoted to reserve roster | | | Before |
| 8/10/1961 | JOL | Estrada | Promoted to active roster | | | Before |
| 8/10/1961 | JOL | Schwall | Demoted to reserve roster | | | Before |
| 8/10/1961 | MAS | Arrigo | Promoted to active roster | | | Before |
| 8/10/1961 | MAS | Haller | Promoted to active roster | | | Before |
| 8/10/1961 | MAS | Nichols | Demoted to reserve roster | | | Before |
| 8/10/1961 | MAS | Sadowski,E | Demoted to reserve roster | | | Before |
| 8/10/1961 | MAS | Smith,HR | Demoted to reserve roster | | | Before |
| 8/10/1961 | MAS | Stallard | Demoted to reserve roster | | | Before |
| 8/10/1961 | MAS | Washburn | Promoted to active roster | | | Before |
| 8/10/1961 | MAS | Zimmerman | Promoted to active roster | | | Before |
| 8/10/1961 | MOU | Hillman | Demoted to reserve roster | | | Before |
| 8/10/1961 | MOU | Tiefenauer | Promoted to active roster | | | Before |
| 8/10/1961 | NEW | Nunn | Demoted to reserve roster | | | Before |
| 8/10/1961 | NEW | Zanni | Promoted to active roster | | | Before |
| 8/14/1961 | JOL | Grba | Demoted to reserve roster | | | Before |
| 8/14/1961 | JOL | McClain | Promoted to active roster | | | Before |
| 8/14/1961 | MAS | Arrigo | Demoted to reserve roster | | | Before |
| 8/14/1961 | MAS | Cisco | Demoted to reserve roster | | | Before |
| 8/14/1961 | MAS | Cisco | Promoted to active roster | | | Before |
| 8/14/1961 | MAS | Haller | Demoted to reserve roster | | | Before |
| 8/14/1961 | MAS | Nichols | Promoted to active roster | | | Before |
| 8/14/1961 | MAS | Sadowski,E | Promoted to active roster | | | Before |
| 8/14/1961 | MAS | Smith,HR | Promoted to active roster | | | Before |
| 8/14/1961 | MAS | Zimmerman | Demoted to reserve roster | | | Before |
| 8/14/1961 | MOU | Bolin | Promoted to active roster | | | Before |
| 8/14/1961 | MOU | Landrith | Promoted to active roster | | | Before |
| 8/14/1961 | MOU | Retzer | Demoted to reserve roster | | | Before |
| 8/14/1961 | MOU | Tiefenauer | Demoted to reserve roster | | | Before |
| 8/17/1961 | ASB | Burgess | Demoted to reserve roster | | | Before |
| 8/17/1961 | ASB | Courtney,C | Promoted to active roster | | | Before |
| 8/17/1961 | ASB | Dobbek | Promoted to active roster | | | Before |
| 8/17/1961 | ASB | Gonzalez | Demoted to reserve roster | | | Before |
| 8/17/1961 | ASB | McAuliffe | Demoted to reserve roster | | | Before |
| 8/17/1961 | ASB | Perry | Promoted to active roster | | | Before |
| 8/17/1961 | EKL | Baumann | Demoted to reserve roster | | | Before |
| 8/17/1961 | EKL | Mincher | Demoted to reserve roster | | | Before |
| 8/17/1961 | EKL | Mincher | Promoted to active roster | | | Before |
| 8/17/1961 | EKL | Woodeshick,H | Promoted to active roster | | | Before |
| 8/17/1961 | FRA | Morton | Promoted to active roster | | | Before |
| 8/17/1961 | FRA | Orsino | Demoted to reserve roster | | | Before |
| 8/17/1961 | FRA | Post | Demoted to reserve roster | | | Before |
| 8/17/1961 | FRA | Roselli | Promoted to active roster | | | Before |
| 8/17/1961 | NBA | Amaro | Demoted to reserve roster | | | Before |
| 8/17/1961 | NBA | Aspromonte,B | Demoted to reserve roster | | | Before |
| 8/17/1961 | NBA | Essegian,C | Demoted to reserve roster | | | Before |
| 8/17/1961 | NBA | Gotay | Promoted to active roster | | | Before |
| 8/17/1961 | NBA | Mantilla | Promoted to active roster | | | Before |
| 8/17/1961 | NBA | Schofield | Promoted to active roster | | | Before |
| 8/17/1961 | RIV | Thomas,L | Demoted to reserve roster | | | Before |
| 8/17/1961 | RIV | Thomas,L | Promoted to active roster | | | Before |
| 8/21/1961 | ASB | Gonzalez | Promoted to active roster | | | Before |
| 8/21/1961 | ASB | Veal | Demoted to reserve roster | | | Before |
| 8/21/1961 | BBC | Craig | Demoted to reserve roster | | | Before |
| 8/21/1961 | BBC | Crandall | Promoted to active roster | | | Before |
| 8/21/1961 | BBC | Ditmar,A | Demoted to reserve roster | | | Before |
| 8/21/1961 | BBC | Harkness | Promoted to active roster | | | Before |
| 8/21/1961 | BBC | Luplow | Promoted to active roster | | | Before |
| 8/21/1961 | BBC | Robinson,Fl | Demoted to reserve roster | | | Before |
| 8/21/1961 | BBC | Roof | Demoted to reserve roster | | | Before |
| 8/21/1961 | BBC | Roof | Promoted to active roster | | | Before |
| 8/21/1961 | BBC | Virdon | Demoted to reserve roster | | | Before |
| 8/21/1961 | BBC | Will | Promoted to active roster | | | Before |
| 8/21/1961 | EKL | Larker | Promoted to active roster | | | Before |
| 8/21/1961 | EKL | Mincher | Demoted to reserve roster | | | Before |
| 8/21/1961 | MOU | Bryan | Promoted to active roster | | | Before |
| 8/21/1961 | MOU | James,C | Demoted to reserve roster | | | Before |
| 8/21/1961 | NBA | Amaro | Promoted to active roster | | | Before |
| 8/21/1961 | NBA | Becquer,J | Promoted to active roster | | | Before |
| 8/21/1961 | NBA | Bressoud | Demoted to reserve roster | | | Before |
| 8/21/1961 | NBA | Bressoud | Promoted to active roster | | | Before |
| 8/21/1961 | NBA | Buchek | Demoted to reserve roster | | | Before |
| 8/21/1961 | NBA | Earley | Demoted to reserve roster | | | Before |
| 8/21/1961 | NBA | Essegian,C | Promoted to active roster | | | Before |
| 8/21/1961 | NBA | MacKenzie,K | Promoted to active roster | | | Before |
| 8/21/1961 | NBA | Neal | Demoted to reserve roster | | | Before |
| 8/21/1961 | NBA | Schofield | Demoted to reserve roster | | | Before |
| 8/21/1961 | TOL | Owens | Promoted to active roster | | | Before |
| 8/21/1961 | TOL | Piersall | Demoted to reserve roster | | | Before |
| 8/24/1961 | BBC | Craig | Promoted to active roster | | | Before |
| 8/24/1961 | BBC | Hiller | Demoted to reserve roster | | | Before |
| 8/24/1961 | BBC | Roof | Promoted to active roster | | | Before |
| 8/24/1961 | BBC | Will | Demoted to reserve roster | | | Before |
| 8/24/1961 | FRA | Bond | Promoted to active roster | | | Before |
| 8/24/1961 | FRA | Bright | Demoted to reserve roster | | | Before |
| 8/24/1961 | FRA | Bright | Promoted to active roster | | | Before |
| 8/24/1961 | FRA | Busby | Demoted to reserve roster | | | Before |
| 8/24/1961 | FRA | Post | Demoted to reserve roster | | | Before |
| 8/24/1961 | FRA | Post | Promoted to active roster | | | Before |
| 8/24/1961 | JOL | McClain | Demoted to reserve roster | | | Before |
| 8/24/1961 | JOL | Schwall | Promoted to active roster | | | Before |
| 8/24/1961 | MAS | Goodman | Demoted to reserve roster | | | Before |
| 8/24/1961 | MAS | Haller | Promoted to active roster | | | Before |
| 8/24/1961 | MAS | Law | Promoted to active roster | | | Before |
| 8/24/1961 | MAS | Smith,HR | Demoted to reserve roster | | | Before |
| 8/24/1961 | NYM | Averill | Demoted to reserve roster | | | Before |
| 8/24/1961 | NYM | Hamilton | Promoted to active roster | | | Before |
| 8/24/1961 | NYM | Heman,R | Demoted to reserve roster | | | Before |
| 8/24/1961 | NYM | LeMay | Demoted to reserve roster | | | Before |
| 8/24/1961 | NYM | McCarver | Promoted to active roster | | | Before |
| 8/24/1961 | NYM | Ortega | Promoted to active roster | | | Before |
| 8/26/1961 | BBC | Ditmar,A | Promoted to active roster | | | Before |
| 8/26/1961 | BBC | Simmons | Demoted to reserve roster | | | Before |
| 8/29/1961 | BBC | Craig | Demoted to reserve roster | | | Before |
| 8/29/1961 | BBC | Crandall | Demoted to reserve roster | | | Before |
| 8/29/1961 | BBC | Harkness | Demoted to reserve roster | | | Before |
| 8/29/1961 | BBC | Hiller | Promoted to active roster | | | Before |
| 8/29/1961 | BBC | Luplow | Demoted to reserve roster | | | Before |
| 8/29/1961 | BBC | Robinson,Fl | Promoted to active roster | | | Before |
| 8/29/1961 | BBC | Roof | Demoted to reserve roster | | | Before |
| 8/29/1961 | BBC | Simmons | Promoted to active roster | | | Before |
| 8/29/1961 | BBC | Virdon | Promoted to active roster | | | Before |
| 8/29/1961 | BBC | Will | Promoted to active roster | | | Before |
| 8/29/1961 | JOL | Bauer | Promoted to active roster | | | Before |
| 8/29/1961 | JOL | Grba | Promoted to active roster | | | Before |
| 8/29/1961 | JOL | Landrum | Promoted to active roster | | | Before |
| 8/29/1961 | JOL | Mahoney | Promoted to active roster | | | Before |
| 8/29/1961 | JOL | McClain | Promoted to active roster | | | Before |
| 8/29/1961 | JOL | Nelson | Promoted to active roster | | | Before |
| 8/29/1961 | JOL | Shoemaker | Promoted to active roster | | | Before |
| 8/29/1961 | MAS | Arrigo | Promoted to active roster | | | Before |
| 8/29/1961 | MAS | Esposito | Promoted to active roster | | | Before |
| 8/29/1961 | MAS | Goodman | Promoted to active roster | | | Before |
| 8/29/1961 | MAS | Law | Demoted to reserve roster | | | Before |
| 8/29/1961 | MAS | Posada | Promoted to active roster | | | Before |
| 8/29/1961 | MAS | Stallard | Promoted to active roster | | | Before |
| 8/29/1961 | MAS | Wickersham | Promoted to active roster | | | Before |
| 8/29/1961 | MAS | Zimmerman | Promoted to active roster | | | Before |
| 8/29/1961 | MOU | Cunningham | Promoted to active roster | | | Before |
| 8/29/1961 | MOU | James,C | Promoted to active roster | | | Before |
| 8/29/1961 | MOU | Sherry,N | Demoted to reserve roster | | | Before |
| 8/29/1961 | NEW | Aguirre | Promoted to active roster | | | Before |
| 8/29/1961 | NEW | Brown,H | Promoted to active roster | | | Before |
| 8/29/1961 | NEW | Fox,T | Promoted to active roster | | | Before |
| 8/29/1961 | NEW | Martin,B | Demoted to reserve roster | | | Before |
| 8/29/1961 | NEW | Roberts | Demoted to reserve roster | | | Before |
| 8/29/1961 | NEW | Roberts | Promoted to active roster | | | Before |
| 8/29/1961 | NYM | Burdette | Promoted to active roster | | | Before |
| 8/29/1961 | NYM | Ortega | Demoted to reserve roster | | | Before |
| 8/29/1961 | NYM | Ortega | Promoted to active roster | | | Before |
| 9/3/1961 | ASB | Burgess | Promoted to active roster | | | Before |
| 9/3/1961 | ASB | Delock | Promoted to active roster | | | Before |
| 9/3/1961 | ASB | Gonder | Promoted to active roster | | | Before |
| 9/3/1961 | ASB | McAuliffe | Promoted to active roster | | | Before |
| 9/3/1961 | ASB | Sadowski,B | Promoted to active roster | | | Before |
| 9/3/1961 | ASB | Veal | Promoted to active roster | | | Before |
| 9/3/1961 | EKL | Baumann | Promoted to active roster | | | Before |
| 9/3/1961 | EKL | Brock | Promoted to active roster | | | Before |
| 9/3/1961 | EKL | Bruce | Promoted to active roster | | | Before |
| 9/3/1961 | EKL | Clendenon | Promoted to active roster | | | Before |
| 9/3/1961 | EKL | Downing | Promoted to active roster | | | Before |
| 9/3/1961 | EKL | Fisher,E | Promoted to active roster | | | Before |
| 9/3/1961 | EKL | Jackson,A | Promoted to active roster | | | Before |
| 9/3/1961 | EKL | Mincher | Promoted to active roster | | | Before |
| 9/3/1961 | EKL | Oliver | Promoted to active roster | | | Before |
| 9/3/1961 | FRA | Busby | Promoted to active roster | | | Before |
| 9/3/1961 | FRA | Malkmus | Promoted to active roster | | | Before |
| 9/3/1961 | FRA | Orsino | Promoted to active roster | | | Before |
| 9/3/1961 | FRA | Piche | Promoted to active roster | | | Before |
| 9/3/1961 | FRA | Post | Promoted to active roster | | | Before |
| 9/3/1961 | FRA | Raymond | Promoted to active roster | | | Before |
| 9/3/1961 | LOU | Reniff | Promoted to active roster | | | Before |
| 9/3/1961 | NBA | Alou,M | Promoted to active roster | | | Before |
| 9/3/1961 | NBA | Aspromonte,B | Promoted to active roster | | | Before |
| 9/3/1961 | NBA | Bressoud | Promoted to active roster | | | Before |
| 9/3/1961 | NBA | Buchek | Promoted to active roster | | | Before |
| 9/3/1961 | NBA | Neal | Promoted to active roster | | | Before |
| 9/3/1961 | NBA | Roebuck | Promoted to active roster | | | Before |
| 9/3/1961 | NBA | Schofield | Promoted to active roster | | | Before |
| 9/3/1961 | NEW | Martin,B | Released | | | Before |
| 9/3/1961 | NEW | Stobbs | Signed | | | Before |
| 9/3/1961 | NEW | Stobbs | Demoted to reserve roster | | | Before |
| 9/3/1961 | NEW | Tanner | Released | | | Before |
| 9/3/1961 | NEW | Tanner | Signed | | | Before |
| 9/3/1961 | NYM | Averill | Promoted to active roster | | | Before |
| 9/3/1961 | NYM | Cline | Promoted to active roster | | | Before |
| 9/3/1961 | NYM | Coker | Promoted to active roster | | | Before |
| 9/3/1961 | NYM | Donovan | Promoted to active roster | | | Before |
| 9/3/1961 | NYM | Heman,R | Promoted to active roster | | | Before |
| 9/3/1961 | NYM | Jay | Promoted to active roster | | | Before |
| 9/3/1961 | NYM | Jones,G | Promoted to active roster | | | Before |
| 9/3/1961 | NYM | LeMay | Promoted to active roster | | | Before |
| 9/3/1961 | NYM | Walters | Promoted to active roster | | | Before |
| 9/3/1961 | RAL | Alusik | Promoted to active roster | | | Before |
| 9/3/1961 | RAL | Brunet | Demoted to reserve roster | | | Before |
| 9/3/1961 | RAL | Callison | Demoted to reserve roster | | | Before |
| 9/3/1961 | RAL | McBean | Demoted to reserve roster | | | Before |
| 9/3/1961 | RAL | Montejo | Promoted to active roster | | | Before |
| 9/3/1961 | RAL | Santo | Demoted to reserve roster | | | Before |
| 9/3/1961 | RAL | Virgil,O | Promoted to active roster | | | Before |
| 9/3/1961 | RIV | Gabler | Demoted to reserve roster | | | Before |
| 9/3/1961 | RIV | Muffett | Promoted to active roster | | | Before |
| 9/4/1961 | TOL | Antonelli,J | Promoted to active roster | | | Before |
| 9/4/1961 | TOL | Aspromonte,K | Promoted to active roster | | | Before |
| 9/4/1961 | TOL | Cardenas | Promoted to active roster | | | Before |
| 9/4/1961 | TOL | Hyde | Promoted to active roster | | | Before |
| 9/4/1961 | TOL | Piersall | Promoted to active roster | | | Before |
| 9/4/1961 | TOL | Schaffernoth,J | Promoted to active roster | | | Before |
| 9/4/1961 | TOL | Schmidt,B | Promoted to active roster | | | Before |
| 9/4/1961 | TOL | Smith,B | Promoted to active roster | | | Before |
| 9/4/1961 | TOL | Tresh | Promoted to active roster | | | Before |
| 9/4/1961 | TOL | Umbricht | Promoted to active roster | | | Before |
| 9/8/1961 | LOU | Gladding | Promoted to active roster | | | Before |
| 9/8/1961 | LOU | Stange | Promoted to active roster | | | Before |
| 9/8/1961 | LOU | Wood,W | Promoted to active roster | | | Before |
| 9/8/1961 | NBA | Buchek | Demoted to reserve roster | | | Before |
| 9/8/1961 | NBA | Gotay | Demoted to reserve roster | | | Before |
| 9/8/1961 | TOL | Tresh | Demoted to reserve roster | | | Before |
| 9/8/1961 | TOL | Umbricht | Demoted to reserve roster | | | Before |
| 9/10/1961 | BBC | Craig | Promoted to active roster | | | Before |
| 9/10/1961 | BBC | Crandall | Promoted to active roster | | | Before |
| 9/10/1961 | BBC | Harkness | Promoted to active roster | | | Before |
| 9/10/1961 | BBC | Maxwell | Promoted to active roster | | | Before |
| 9/10/1961 | BBC | Satriano | Promoted to active roster | | | Before |
| 9/10/1961 | BBC | Thacker | Promoted to active roster | | | Before |
| 9/10/1961 | FRA | Mejias | Promoted to active roster | | | Before |
| 9/10/1961 | FRA | Orsino | Demoted to reserve roster | | | Before |
| 9/10/1961 | FRA | White,S | Promoted to active roster | | | Before |
| 9/10/1961 | JOL | Horlen | Promoted to active roster | | | Before |
| 9/10/1961 | JOL | Koplitz | Promoted to active roster | | | Before |
| 9/10/1961 | LOU | Clinton | Promoted to active roster | | | Before |
| 9/10/1961 | LOU | Kaat | Demoted to reserve roster | | | Before |
| 9/10/1961 | LOU | Schaffer | Promoted to active roster | | | Before |
| 9/10/1961 | LOU | Stange | Demoted to reserve roster | | | Before |
| 9/10/1961 | LOU | Wood,W | Demoted to reserve roster | | | Before |
| 9/10/1961 | MOU | Cannizzaro | Promoted to active roster | | | Before |
| 9/10/1961 | MOU | Sherry,N | Promoted to active roster | | | Before |
| 9/10/1961 | NYM | Averill | Promoted to active roster | | | Before |
| 9/10/1961 | NYM | Cline | Promoted to active roster | | | Before |
| 9/10/1961 | NYM | Coker | Promoted to active roster | | | Before |
| 9/10/1961 | NYM | Donovan | Promoted to active roster | | | Before |
| 9/10/1961 | NYM | Heman,R | Promoted to active roster | | | Before |
| 9/10/1961 | NYM | Jones,G | Promoted to active roster | | | Before |
| 9/10/1961 | NYM | LeMay | Promoted to active roster | | | Before |
| 9/10/1961 | NYM | Walters | Promoted to active roster | | | Before |
| 9/11/1961 | MOU | Cannizzaro | Demoted to reserve roster | | | Before |
| 9/14/1961 | BBC | Craig | Demoted to reserve roster | | | Before |
| 9/14/1961 | BBC | Crandall | Demoted to reserve roster | | | Before |
| 9/14/1961 | BBC | Harkness | Demoted to reserve roster | | | Before |
| 9/14/1961 | JOL | Horlen | Demoted to reserve roster | | | Before |
| 9/14/1961 | JOL | Koplitz | Demoted to reserve roster | | | Before |
| 9/14/1961 | NEW | Brinkman | Demoted to reserve roster | | | Before |
| 9/14/1961 | NEW | Kluszewski | Demoted to reserve roster | | | Before |
| 9/14/1961 | NEW | McDowell | Demoted to reserve roster | | | Before |
| 9/14/1961 | NEW | Nunn | Demoted to reserve roster | | | Before |
| 9/14/1961 | NEW | Powell | Demoted to reserve roster | | | Before |
| 9/14/1961 | NEW | Zanni | Demoted to reserve roster | | | Before |
| 9/17/1961 | RIV | Adair | Demoted to reserve roster | | | Before |
| 9/17/1961 | RIV | Chance | Promoted to active roster | | | Before |
| 9/17/1961 | RIV | Clevenger,T | Promoted to active roster | | | Before |
| 9/17/1961 | RIV | Gabler | Promoted to active roster | | | Before |
| 9/17/1961 | RIV | Hershberger | Promoted to active roster | | | Before |
| 9/17/1961 | RIV | Howard,F | Promoted to active roster | | | Before |
| 9/17/1961 | RIV | Kubek | Promoted to active roster | | | Before |
| 9/17/1961 | RIV | Nischwitz | Promoted to active roster | | | Before |
| 9/17/1961 | RIV | Osteen,C | Promoted to active roster | | | Before |
| 9/17/1961 | RIV | Thomas,L | Promoted to active roster | | | Before |
| 9/17/1961 | TOL | Tresh | Promoted to active roster | | | Before |
| 9/17/1961 | TOL | Umbricht | Promoted to active roster | | | Before |
| 9/21/1961 | TOL | Spencer,D | Demoted to reserve roster | | | Before |
| 9/21/1961 | TOL | Tresh | Demoted to reserve roster | | | Before |
| 9/21/1961 | TOL | Umbricht | Demoted to reserve roster | | | Before |
| 9/21/1961 | TOL | Woodling | Demoted to reserve roster | | | Before |
| 9/24/1961 | BBC | Craig | Promoted to active roster | | | Before |
| 9/24/1961 | BBC | Crandall | Promoted to active roster | | | Before |
| 9/24/1961 | BBC | Harkness | Demoted to reserve roster | | | Before |
| 9/24/1961 | BBC | Harkness | Promoted to active roster | | | Before |
| 9/24/1961 | FRA | Morton | Demoted to reserve roster | | | Before |
| 9/24/1961 | JOL | Horlen | Promoted to active roster | | | Before |
| 9/24/1961 | JOL | Koplitz | Promoted to active roster | | | Before |
| 9/24/1961 | MAS | Goodman | Demoted to reserve roster | | | Before |
| 9/24/1961 | MAS | Law | Promoted to active roster | | | Before |
| 9/24/1961 | MAS | Pearson | Demoted to reserve roster | | | Before |
| 9/24/1961 | NBA | Becquer,J | Demoted to reserve roster | | | Before |
| 9/24/1961 | NBA | Becquer,J | Promoted to active roster | | | Before |
| 9/24/1961 | NBA | Essegian,C | Demoted to reserve roster | | | Before |
| 9/24/1961 | NBA | MacKenzie,K | Demoted to reserve roster | | | Before |
| 9/24/1961 | NBA | Roebuck | Demoted to reserve roster | | | Before |
| 9/24/1961 | NEW | Brinkman | Promoted to active roster | | | Before |
| 9/24/1961 | NEW | Nunn | Promoted to active roster | | | Before |
| 9/24/1961 | NEW | Powell | Promoted to active roster | | | Before |
| 9/24/1961 | NEW | Zanni | Promoted to active roster | | | Before |
| 9/24/1961 | RAL | Virgil,O | Demoted to reserve roster | | | Before |
| 9/24/1961 | RIV | Torre | Demoted to reserve roster | | | Before |
| 9/25/1961 | NEW | Zanni | Demoted to reserve roster | | | Before |
| 9/28/1961 | FRA | Mejias | Demoted to reserve roster | | | Before |
| 9/28/1961 | FRA | Mejias | Promoted to active roster | | | Before |
| 9/28/1961 | NEW | Philley | Demoted to reserve roster | | | Before |
| 9/28/1961 | NEW | Sawatski | Demoted to reserve roster | | | Before |
| 9/28/1961 | NEW | Sawatski | Promoted to active roster | | | Before |
| 9/28/1961 | NEW | Schroll | Demoted to reserve roster | | | Before |
| 9/28/1961 | NEW | Thomas,V | Demoted to reserve roster | | | Before |
| 9/29/1961 | BBC | Craig | Demoted to reserve roster | | | Before |
| 9/29/1961 | BBC | Crandall | Demoted to reserve roster | | | Before |
| 9/29/1961 | BBC | Satriano | Demoted to reserve roster | | | Before |
| 9/29/1961 | BBC | Satriano | Promoted to active roster | | | Before |
| 9/29/1961 | FRA | Camilli | Promoted to active roster | | | Before |
| 9/29/1961 | FRA | Camilli | Placed on Injured List | | 9/30/1961 | Before |
| 9/29/1961 | FRA | Morton | Promoted to active roster | | | Before |
| 9/29/1961 | FRA | Morton | Placed on Injured List | | 9/30/1961 | Before |
| 9/29/1961 | FRA | Orsino | Promoted to active roster | | | Before |
| 9/29/1961 | FRA | Orsino | Placed on Injured List | | 9/30/1961 | Before |
| 9/29/1961 | JOL | Horlen | Demoted to reserve roster | | | Before |
| 9/29/1961 | MAS | Arrigo | Demoted to reserve roster | | | Before |
| 9/29/1961 | MAS | Law | Demoted to reserve roster | | | Before |
| 9/29/1961 | MAS | Pearson | Promoted to active roster | | | Before |
| 9/29/1961 | MOU | Bryan | Demoted to reserve roster | | | Before |
| 9/29/1961 | MOU | Pappas | Demoted to reserve roster | | | Before |
| 9/29/1961 | MOU | Retzer | Demoted to reserve roster | | | Before |
| 9/29/1961 | NEW | Bridges,M | Demoted to reserve roster | | | Before |
| 9/29/1961 | NEW | Brinkman | Demoted to reserve roster | | | Before |
| 9/29/1961 | NEW | Grammas | Demoted to reserve roster | | | Before |
| 9/29/1961 | NEW | Nunn | Demoted to reserve roster | | | Before |
| 9/29/1961 | NEW | Powell | Demoted to reserve roster | | | Before |
| 9/29/1961 | NYM | Jay | Promoted to active roster | | | Before |
| 10/3/1961 | BBC | Anderson,C | Promoted to active roster | | | Before |
| 10/3/1961 | BBC | Anderson,C | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | BBC | Craig | Promoted to active roster | | | Before |
| 10/3/1961 | BBC | Craig | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | FRA | Bond | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | FRA | Mejias | Demoted to reserve roster | | | Before |
| 10/3/1961 | FRA | White,S | Demoted to reserve roster | | | Before |
| 10/3/1961 | MAS | Goodman | Promoted to active roster | | | Before |
| 10/3/1961 | MAS | Goodman | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | MOU | Pappas | Promoted to active roster | | | Before |
| 10/3/1961 | MOU | Pappas | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | NBA | Brewer,T | Promoted to active roster | | | Before |
| 10/3/1961 | NBA | Brewer,T | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | NBA | Buchek | Promoted to active roster | | | Before |
| 10/3/1961 | NBA | Gotay | Promoted to active roster | | | Before |
| 10/3/1961 | NEW | Gardner,B | Signed | | | Before |
| 10/3/1961 | NEW | McDowell | Promoted to active roster | | | Before |
| 10/3/1961 | NEW | McDowell | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | NEW | Philley | Released | | | Before |
| 10/3/1961 | NEW | Roarke | Signed | | | Before |
| 10/3/1961 | NEW | Sadowski,T | Signed | | | Before |
| 10/3/1961 | NEW | Schroll | Released | | | Before |
| 10/3/1961 | NEW | Thomas,V | Released | | | Before |
| 10/3/1961 | RAL | Brunet | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Brunet | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | RAL | Callison | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Cheney,T | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Flood | Demoted to reserve roster | | | Before |
| 10/3/1961 | RAL | Flood | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Flood | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | RAL | Fregosi | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Hook | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Kindall | Demoted to reserve roster | | | Before |
| 10/3/1961 | RAL | Kindall | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Kindall | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | RAL | Marichal | Demoted to reserve roster | | | Before |
| 10/3/1961 | RAL | Marichal | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Marichal | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | RAL | Peters | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Santo | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Virgil,O | Demoted to reserve roster | | | Before |
| 10/3/1961 | RAL | Virgil,O | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Virgil,O | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | RAL | Windhorn | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Wyatt | Promoted to active roster | | | Before |
| 10/3/1961 | RAL | Wyatt | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | RIV | Adair | Promoted to active roster | | | Before |
| 10/3/1961 | RIV | Adair | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | RIV | Hershberger | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | RIV | McCovey | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | RIV | Torre | Placed on Injured List | | 9/30/1961 | Before |
| 10/3/1961 | TOL | Woodling | Promoted to active roster | | | Before |
| 10/3/1961 | TOL | Woodling | Placed on Injured List | | 9/30/1961 | Before |
| 10/8/1961 | ASB | Gonder | Demoted to reserve roster | | | Before |
| 10/8/1961 | EKL | Hobbie | Demoted to reserve roster | | | Before |
| 10/8/1961 | NBA | Essegian,C | Promoted to active roster | | | Before |
| 10/8/1961 | RAL | Cheney,T | Demoted to reserve roster | | | Before |
| 10/8/1961 | RAL | McBean | Promoted to active roster | | | Before |
| 10/10/1961 | BBC | Crandall | Promoted to active roster | | | Before |
| 10/10/1961 | BBC | Harkness | Promoted to active roster | | | Before |
| 10/10/1961 | BBC | Luplow | Promoted to active roster | | | Before |
| 10/10/1961 | FRA | Mejias | Promoted to active roster | | | Before |
| 10/10/1961 | FRA | White,S | Promoted to active roster | | | Before |
| 10/10/1961 | JOL | Horlen | Promoted to active roster | | | Before |
| 10/10/1961 | JOL | Shoemaker | Placed on Injured List | | 10/9/1961 | Before |
| 10/10/1961 | LOU | Christopher | Released | | | Before |
| 10/10/1961 | LOU | Clinton | Demoted to reserve roster | | | Before |
| 10/10/1961 | LOU | Clinton | Promoted to active roster | | | Before |
| 10/10/1961 | LOU | Coleman,C | Demoted to reserve roster | | | Before |
| 10/10/1961 | LOU | Coleman,C | Promoted to active roster | | | Before |
| 10/10/1961 | LOU | Drysdale | Demoted to reserve roster | | | Before |
| 10/10/1961 | LOU | Gladding | Demoted to reserve roster | | | Before |
| 10/10/1961 | LOU | Grzenda | Signed | | | Before |
| 10/10/1961 | LOU | Grzenda | Demoted to reserve roster | | | Before |
| 10/10/1961 | LOU | Hubbs | Promoted to active roster | | | Before |
| 10/10/1961 | LOU | Kaat | Promoted to active roster | | | Before |
| 10/10/1961 | LOU | Krausse | Demoted to reserve roster | | | Before |
| 10/10/1961 | LOU | Krausse | Promoted to active roster | | | Before |
| 10/10/1961 | LOU | Mathews,N | Signed | | | Before |
| 10/10/1961 | LOU | Mathews,N | Demoted to reserve roster | | | Before |
| 10/10/1961 | LOU | Pfister | Signed | | | Before |
| 10/10/1961 | LOU | Pfister | Demoted to reserve roster | | | Before |
| 10/10/1961 | LOU | Schaffer | Released | | | Before |
| 10/10/1961 | LOU | Thomas,G | Released | | | Before |
| 10/10/1961 | MAS | Buhl | Demoted to reserve roster | | | Before |
| 10/10/1961 | MAS | O'Connell | Placed on Injured List | | 10/9/1961 | Before |
| 10/10/1961 | MAS | Rollins | Promoted to active roster | | | Before |
| 10/10/1961 | MAS | Smith,HR | Promoted to active roster | | | Before |
| 10/10/1961 | MAS | Spangler | Demoted to reserve roster | | | Before |
| 10/10/1961 | MOU | Hillman | Promoted to active roster | | | Before |
| 10/10/1961 | RAL | Cheney,T | Promoted to active roster | | | Before |
| 10/10/1961 | RAL | Cheney,T | Placed on Injured List | | 10/9/1961 | Before |
| 10/10/1961 | TOL | Bowman | Signed | | | Before |
| 10/10/1961 | TOL | Cardenas | Demoted to reserve roster | | | Before |
| 10/10/1961 | TOL | Davenport | Demoted to reserve roster | | | Before |
| 10/10/1961 | TOL | Hamlin | Placed on Injured List | | 10/9/1961 | Before |
| 10/10/1961 | TOL | Piersall | Demoted to reserve roster | | | Before |
| 10/10/1961 | TOL | Schaffernoth,J | Released | | | Before |
| 10/10/1961 | TOL | Smith,HW | Demoted to reserve roster | | | Before |
| 10/10/1961 | TOL | Wynn | Demoted to reserve roster | | | Before |
| 10/11/1961 | RIV | Killebrew | Demoted to reserve roster | | | Before |
| 10/12/1961 | MAS | Washburn | Demoted to reserve roster | | | Before |
| 10/17/1961 | LOU | Drysdale | Promoted to active roster | | | Before |
| 10/17/1961 | LOU | Krausse | Demoted to reserve roster | | | Before |