| Name | Name | K |
| Sandy Koufax* | Tarheels | 263 |
| Camilo Pascual | Ahabs | 200 |
| Stan Williams | Lightning | 193 |
| Mike McCormick* | Robbers | 181 |
| Jim O'Toole* | Saints | 179 |
| Art Mahaffey | Tigers | 178 |
| Joe Gibbon* | Robbers | 171 |
| Bob Gibson | Lightning | 171 |
| Ken McBride | Rockets | 152 |
| Bill Monbouquette | Bears | 150 |
| Gary Bell | Ahabs | 148 |
| Don Mossi* | Tigers | 142 |
| Pedro Ramos | Black Cats | 142 |
| Chuck Estrada | Jakes | 140 |
| Jim Archer* | Frigates | 136 |
| Jack Kralick* | Black Cats | 135 |
| Jim Kaat* | Lightning | 134 |
| Don Cardwell | Mets | 131 |
| Don Drysdale | Lightning | 130 |
| Juan Pizarro* | Lakers | 130 |
| Frank Lary | Tigers | 129 |
| Jim Bunning | Frigates | 118 |
| Ernie Broglio | Saints | 116 |
| Steve Barber* | Saints | 111 |
| Jack Fisher | Argonauts | 111 |
| Barry Latman | Rockets | 110 |
| Ray Sadecki* | Bears | 109 |
| Whitey Ford* | Mets | 107 |
| Bob Friend | Black Cats | 105 |
| Juan Marichal | Tarheels | 105 |
| Billy Pierce* | Frigates | 104 |
| Harvey Haddix* | Bears | 102 |
| Bill Stafford | Jakes | 100 |
| Billy O'Dell* | Rockets | 98 |
| Milt Pappas | Saints | 95 |
| Bob Purkey | Frigates | 95 |
| Curt Simmons* | Black Cats | 95 |
| Ryne Duren | Lakers | 95 |
| Bennie Daniels | Rockets | 94 |
| Ken Hunt | Tarheels | 92 |
| Don Schwall | Jakes | 92 |
| Glen Hobbie | Lakers | 89 |
| Ralph Terry | Robbers | 89 |
| Warren Spahn* | Lakers | 88 |
| Ray Herbert | Ahabs | 88 |
| Ted Bowsfield* | Frigates | 87 |
| Joey Jay | Mets | 87 |
| Gene Conley | Argonauts | 86 |
| Mudcat Grant | Lakers | 86 |
| Joe Nuxhall* | Lakers | 86 |
| Tracy Stallard | Tigers | 86 |
| Paul Foytack | Bears | 84 |
| Tom Sturdivant | Argonauts | 80 |
| Dick Ellsworth* | Argonauts | 77 |
| Dick Hall | Ahabs | 77 |
| Sam Jones | Black Cats | 76 |
| Ron Moeller* | Tarheels | 74 |
| Early Wynn | Rockets | 72 |
| Bob Buhl | Tigers | 70 |
| Cal McLish | Ahabs | 70 |
| Carl Willey | Robbers | 70 |
| Dick Donovan | Mets | 69 |
| Ed Rakow | Lightning | 69 |
| Luis Arroyo* | Jakes | 68 |
| Johnny Podres* | Mets | 68 |
| Ed Hobaugh | Rockets | 67 |
| Billy Hoeft* | Mets | 66 |
| Jim Maloney | Tarheels | 65 |
| Jim Perry | Argonauts | 64 |
| Pete Burnside* | Frigates | 63 |
| Art Fowler | Jakes | 63 |
| Jack Sanford | Lakers | 63 |
| Turk Farrell | Mets | 63 |
| Hoyt Wilhelm | Rockets | 62 |
| Larry Jackson | Lakers | 61 |
| John Buzhardt | Jakes | 60 |
| Jim Coates | Ahabs | 60 |
| Barney Schultz | Mets | 60 |
| Eli Grba | Jakes | 58 |
| Stu Miller | Tigers | 58 |
| Bobby Shantz* | Ahabs | 58 |
| Norm Bass | Ahabs | 56 |
| Frank Sullivan | Robbers | 56 |
| Jack Curtis* | Tarheels | 55 |
| Mike Fornieles | Rockets | 55 |
| Chris Short* | Tarheels | 55 |
| Bud Daley* | Jakes | 55 |
| Jim Donohue | Robbers | 55 |
| Rollie Sheldon | Lightning | 54 |
| Frank Baumann* | Lakers | 53 |
| Roger Craig | Black Cats | 52 |
| Don Elston | Frigates | 52 |
| Frank Funk | Jakes | 52 |
| Bob Hendley* | Saints | 51 |
| Don Lee | Lightning | 50 |
| Bob Anderson | Robbers | 49 |
| Hal Brown | Bears | 49 |
| Lew Burdette | Mets | 49 |
| Robin Roberts | Bears | 49 |
| Larry Sherry | Lightning | 49 |
| Arnold Earley* | Ahabs | 47 |
| Wynn Hawkins | Saints | 47 |
| Al McBean | Tarheels | 47 |
| Wes Stock | Robbers | 47 |
| Tony Cloninger | Argonauts | 46 |
| Joe McClain | Jakes | 45 |
| Don Nottebart | Black Cats | 45 |
| Bill Henry* | Tigers | 44 |
| Dave Hillman | Saints | 44 |
| Bob Shaw | Robbers | 44 |
| Marty Kutyna | Rockets | 43 |
| Bobby Bolin | Saints | 42 |
| Turk Lown | Tigers | 42 |
| Billy Loes | Saints | 41 |
| Clem Labine | Argonauts | 40 |
| Ron Perranoski* | Frigates | 40 |
| Jerry Casale | Argonauts | 40 |
| Roy Face | Black Cats | 39 |
| Jerry Walker | Argonauts | 39 |
| Earl Francis | Ahabs | 38 |
| Tom Morgan | Jakes | 38 |
| Ken Johnson | Mets | 38 |
| Don Larsen | Jakes | 37 |
| Al Cicotte | Bears | 36 |
| Jay Hook | Tarheels | 36 |
| Jack Baldschun | Rockets | 35 |
| Vinegar Bend Mizell* | Saints | 35 |
| Ray Moore | Bears | 35 |
| Johnny James | Saints | 35 |
| Jim Duffalo | Tarheels | 34 |
| Jim Brewer* | Mets | 33 |
| Hank Aguirre* | Bears | 32 |
| Art Ditmar | Black Cats | 32 |
| Gerry Staley | Argonauts | 32 |
| Ike Delock | Argonauts | 31 |
| Johnny Klippstein | Argonauts | 31 |
| Lindy McDaniel | Lightning | 31 |
| Don McMahon | Bears | 31 |
| Ron Kline | Mets | 31 |
| Dave Sisler | Frigates | 30 |
| Warren Hacker | Frigates | 29 |
| Phil Regan | Argonauts | 29 |
| Dick Stigman* | Robbers | 29 |
| Sherman Jones | Black Cats | 27 |
| Bobby Locke | Saints | 27 |
| Bob Miller | Ahabs | 27 |
| Tom Cheney | Tarheels | 27 |
| Hal Woodeshick* | Lakers | 26 |
| Jim Brosnan | Jakes | 25 |
| Dick Drott | Rockets | 25 |
| Dallas Green | Lakers | 25 |
| Terry Fox | Bears | 24 |
| Chet Nichols* | Tigers | 24 |
| Jack Spring* | Frigates | 24 |
| Al Schroll | Bears | 23 |
| Bill Fischer | Tarheels | 23 |
| Bob Allen* | Robbers | 21 |
| Bob Bruce | Lakers | 21 |
| John Gabler | Robbers | 21 |
| Bob Turley | Argonauts | 21 |
| Don Ferrarese* | Lightning | 19 |
| Jim Owens | Rockets | 19 |
| Hal Reniff | Lightning | 19 |
| Claude Raymond | Frigates | 18 |
| Manny Montejo | Tarheels | 17 |
| Craig Anderson | Black Cats | 16 |
| Russ Kemmerer | Lightning | 16 |
| Lew Krausse | Lightning | 16 |
| Bill Pleis* | Robbers | 16 |
| Danny McDevitt* | Saints | 16 |
| Eddie Fisher | Lakers | 15 |
| Bill Kunkel | Tarheels | 15 |
| Vern Law | Tigers | 15 |
| Marshall Bridges* | Bears | 14 |
| Jim Golden | Black Cats | 14 |
| Dick LeMay* | Mets | 14 |
| Billy Muffett | Robbers | 14 |
| Howie Nunn | Bears | 14 |
| Phil Ortega | Mets | 13 |
| Tom Brewer | Ahabs | 12 |
| Mike Garcia | Black Cats | 12 |
| Ed Bauta | Tarheels | 11 |
| Al Jackson* | Lakers | 11 |
| John Wyatt | Tarheels | 11 |
| Al Downing* | Lakers | 9 |
| Ron Piche | Frigates | 9 |
| Chuck Stobbs* | Bears | 9 |
| Galen Cisco | Tigers | 8 |
| Steve Hamilton* | Mets | 8 |
| Ray Washburn | Tigers | 8 |
| Dom Zanni | Bears | 8 |
| Sam McDowell* | Bears | 7 |
| Tex Clevenger | Robbers | 7 |
| Mickey McDermott* | Black Cats | 7 |
| Gerry Arrigo* | Tigers | 5 |
| Howie Koplitz | Jakes | 5 |
| Gary Peters* | Tarheels | 5 |
| Ed Roebuck | Ahabs | 5 |
| Dave Wickersham | Tigers | 5 |
| Bill Dailey | Saints | 4 |
| Ned Garver | Bears | 4 |
| Ken MacKenzie* | Ahabs | 4 |
| Moe Drabowsky | Lakers | 3 |
| Bobby Tiefenauer | Saints | 3 |
| Johnny Antonelli* | Rockets | 3 |
| Russ Heman | Mets | 3 |
| George Brunet* | Tarheels | 2 |
| Dean Chance | Robbers | 2 |
| Dick Hyde | Rockets | 2 |
| Ken Lehman* | Lightning | 2 |
| Ron Nischwitz* | Robbers | 2 |
| Jim Umbricht | Rockets | 2 |
| Joe Horlen | Jakes | 1 |
| Fred Gladding | Lightning | 0 |
| Chi-chi Olivo | Argonauts | 0 |
| Ted Sadowski | Bears | 0 |
| Joe Schaffernoth | Rockets | 0 |