| Name | Name | K |
| Gaylord Perry | Grays | 102 |
| Sam McDowell* | Bears | 75 |
| Sandy Koufax* | Tarheels | 73 |
| Jim Maloney | Tarheels | 73 |
| Luis Tiant | Bullies | 68 |
| Jim Kaat* | Scouts | 66 |
| Dean Chance | Frigates | 65 |
| Mel Stottlemyre | Jakes | 65 |
| Bob Veale* | Scouts | 65 |
| Earl Wilson | Bombers | 62 |
| Jim Bunning | Tarheels | 61 |
| Chris Short* | Rockets | 61 |
| Denny Lemaster* | Rockets | 60 |
| Dave Boswell | Frigates | 59 |
| Juan Marichal | Tarheels | 59 |
| Bob Gibson | Scouts | 58 |
| Mike Cuellar* | Bears | 57 |
| Don Sutton | Scouts | 57 |
| Gary Peters* | Tarheels | 55 |
| Pete Richert* | Tourists | 54 |
| Mickey Lolich* | Argonauts | 52 |
| Tommy John* | Rockets | 47 |
| Jim O'Toole* | Tourists | 47 |
| Claude Osteen* | Bombers | 44 |
| Bobby Bolin | Tourists | 42 |
| Marcelino Lopez* | Bears | 42 |
| Dave McNally* | Bears | 42 |
| Phil Ortega | Mets | 42 |
| Bill Hands | Jakes | 41 |
| Steve Barber* | Tourists | 40 |
| Denny McLain | Bears | 40 |
| Milt Pappas | Tourists | 40 |
| Tony Cloninger | | 39 |
| Woodie Fryman* | Colonels | 39 |
| Jim Merritt* | Rockets | 39 |
| Ray Washburn | Frigates | 39 |
| Jim Palmer | Tigers | 38 |
| Larry Jaster* | Black Cats | 37 |
| Ken Johnson | Mets | 37 |
| Jim Nash | Grays | 37 |
| Joe Nuxhall* | Bullies | 37 |
| Don Drysdale | Bombers | 36 |
| Dick Ellsworth* | Argonauts | 36 |
| Dave Giusti | Bullies | 36 |
| Ken Holtzman* | Black Cats | 35 |
| Bucky Brandon | Mets | 34 |
| Don Cardwell | Mets | 34 |
| Jim Perry | Argonauts | 34 |
| Sonny Siebert | Colt .45's | 34 |
| Moe Drabowsky | Jakes | 33 |
| Steve Hargan | Colt .45's | 33 |
| Lee Stange | Tigers | 33 |
| Pat Jarvis | Jakes | 32 |
| Jack Fisher | Argonauts | 31 |
| Vern Law | Tigers | 31 |
| Joe Horlen | Colt .45's | 30 |
| Bruce Howard | Argonauts | 30 |
| Ken Sanders | Mets | 30 |
| Cal Koonce | Grays | 29 |
| Fergie Jenkins | Colt .45's | 29 |
| Don Schwall | Jakes | 29 |
| Nelson Briles | Colonels | 28 |
| George Brunet* | Bullies | 28 |
| Larry Dierker | Scouts | 28 |
| Sammy Ellis | Colonels | 28 |
| Jim Hannan | Black Cats | 28 |
| Bob Shaw | Colonels | 28 |
| Gary Bell | Bombers | 27 |
| Wally Bunker | Colonels | 27 |
| John Buzhardt | Jakes | 27 |
| Whitey Ford* | Rockets | 27 |
| Lew Krausse | Rockets | 27 |
| Mike McCormick* | Bombers | 27 |
| Hank Fischer | Jakes | 27 |
| Fred Talbot | Grays | 27 |
| Bob Humphreys | Mets | 26 |
| Lindy McDaniel | Frigates | 26 |
| Larry Sherry | Tigers | 26 |
| Ray Sadecki* | Black Cats | 26 |
| Pete Cimino | Grays | 25 |
| Fred Gladding | Bullies | 25 |
| Dave Wickersham | Rockets | 25 |
| Joey Jay | Grays | 25 |
| Al Downing* | Colt .45's | 24 |
| Jack Hamilton | Argonauts | 24 |
| Al Jackson* | Tigers | 24 |
| Fritz Peterson* | Frigates | 24 |
| Hal Reniff | Argonauts | 24 |
| Jerry Stephenson | Jakes | 24 |
| Roy Face | Argonauts | 23 |
| Turk Farrell | Colt .45's | 23 |
| Rob Gardner* | Tigers | 23 |
| Jim McGlothlin | Grays | 23 |
| Dennis Higgins | Bullies | 22 |
| Jim Lonborg | Colt .45's | 22 |
| Bob Priddy | Bullies | 22 |
| Al Worthington | Scouts | 22 |
| Eddie Fisher | Mets | 22 |
| Bob Friend | Black Cats | 22 |
| Darold Knowles* | Black Cats | 21 |
| Steve Blass | Black Cats | 20 |
| Phil Regan | Black Cats | 20 |
| Hoyt Wilhelm | Scouts | 20 |
| Johnny Podres* | Mets | 20 |
| Joe Hoerner* | Mets | 19 |
| Bill Monbouquette | Frigates | 19 |
| Jay Ritchie | Tourists | 19 |
| Stu Miller | Bears | 18 |
| Bob Buhl | Tigers | 18 |
| Pete Mikkelsen | Bombers | 17 |
| Bob Miller | Bullies | 17 |
| John Miller | Tourists | 17 |
| Fred Newman | Colonels | 17 |
| Jim Owens | Rockets | 17 |
| Ron Perranoski* | Black Cats | 17 |
| Clay Carroll | Rockets | 16 |
| Steve Hamilton* | Bullies | 16 |
| Jack Kralick* | Argonauts | 16 |
| Larry Jackson | | 16 |
| Dick Radatz | Bombers | 16 |
| Jack Aker | Colt .45's | 15 |
| Blue Moon Odom | Colonels | 15 |
| Rick Wise | Colt .45's | 15 |
| Mudcat Grant | Colt .45's | 14 |
| Barry Latman | Rockets | 14 |
| Barry Moore* | Jakes | 14 |
| Chi-Chi Olivo | Bears | 14 |
| Dan Osinski | Tigers | 14 |
| Diego Segui | Tigers | 14 |
| Bob Allen* | Jakes | 13 |
| Catfish Hunter | Bombers | 13 |
| Paul Lindblad* | Colonels | 13 |
| Orlando Pena | Mets | 13 |
| Jose Santiago | Tarheels | 13 |
| Dick Selma | Grays | 13 |
| Eddie Watt | Scouts | 13 |
| Don McMahon | Scouts | 13 |
| Curt Simmons* | Argonauts | 13 |
| Joe Gibbon* | Grays | 12 |
| Ron Herbel | Mets | 12 |
| Bob Lee | Frigates | 12 |
| Frank Linzy | Bombers | 12 |
| Minnie Rojas | Colonels | 12 |
| Rollie Sheldon | Bullies | 12 |
| Gene Brabender | Colonels | 11 |
| Dennis Ribant | Frigates | 11 |
| Ted Abernathy | Tarheels | 11 |
| John Wyatt | Tarheels | 11 |
| Tom Kelley | Tourists | 10 |
| Joe Moeller | Tigers | 10 |
| Don Nottebart | Grays | 10 |
| Claude Raymond | Frigates | 10 |
| Dooley Womack | Scouts | 10 |
| Larry Bearnarth | Grays | 9 |
| Jim Bouton | Tourists | 9 |
| Bob Hendley* | Tourists | 9 |
| Arnold Umbach | Black Cats | 9 |
| Frank Bertaina* | Frigates | 8 |
| Casey Cox | Bombers | 8 |
| Jack Lamabe | Tourists | 8 |
| Billy McCool* | Tarheels | 8 |
| Tug McGraw* | Colt .45's | 8 |
| Rich Nye* | Grays | 8 |
| Juan Pizarro* | Colt .45's | 8 |
| Jack Sanford | Tigers | 8 |
| Luke Walker* | Black Cats | 8 |
| Hal Woodeshick* | Scouts | 8 |
| Terry Fox | Rockets | 8 |
| Billy Hoeft* | Grays | 8 |
| Hank Aguirre* | Bears | 7 |
| Dennis Bennett* | Argonauts | 7 |
| Wade Blasingame* | Colonels | 7 |
| Don Dennis | Bullies | 7 |
| Arnold Earley* | Tourists | 7 |
| Johnny Klippstein | Bears | 7 |
| Al McBean | Tarheels | 7 |
| Dick Stigman* | Bombers | 7 |
| Gerry Arrigo* | Tigers | 7 |
| Bill Short* | Bullies | 7 |
| Jack Baldschun | Tigers | 6 |
| Lew Burdette | Jakes | 6 |
| Ray Culp | Frigates | 6 |
| Dick Lines* | Tarheels | 6 |
| Tommie Sisk | Colonels | 6 |
| Joe Sparma | Tourists | 6 |
| Billy O'Dell* | Rockets | 6 |
| Ted Davidson* | Bears | 5 |
| Dick Hall | Bears | 5 |
| Bill Henry* | Tigers | 5 |
| Dick Kelley* | Grays | 5 |
| Bob Locker | Scouts | 5 |
| Ralph Terry | Bombers | 5 |
| Bob Bruce | Colt .45's | 4 |
| Bill Hepler* | Bullies | 4 |
| Ron Kline | Mets | 4 |
| Jim Ollom* | Argonauts | 4 |
| Wes Stock | Frigates | 4 |
| Clyde Wright* | Bears | 4 |
| Dave Baldwin | Grays | 3 |
| Jim Coates | Grays | 2 |
| George Culver | Colt .45's | 2 |
| John O'Donoghue* | Tourists | 2 |
| Chuck Hartenstein | Grays | 1 |
| Fred Klages | Argonauts | 1 |
| Mel Queen | Black Cats | 1 |
| Pedro Ramos | Frigates | 1 |
| Chuck Dobson | Colonels | 0 |