| Name | Name | ERA |
| Emil Bildilli* | Sprudels | 0.00 |
| Dizzy Trout | Bean Brewers | 0.60 |
| Carl Hubbell* | Mutuals | 0.67 |
| Chubby Dean* | Bean Brewers | 1.17 |
| Luke Hamlin | Mutuals | 1.23 |
| Emerson Dickman | Whiffenpoofs | 1.42 |
| Lefty Gomez* | Mutuals | 1.44 |
| Jack Wilson | Sprudels | 1.46 |
| Tommy Bridges | Glaziers | 1.59 |
| Johnny Vander Meer* | Titans | 1.65 |
| Hugh Mulcahy | Frogs | 1.69 |
| Johnny Rigney | Dodgers | 1.93 |
| Willis Hudlin | Seals | 2.00 |
| Rip Sewell | Blue Sox | 2.16 |
| Johnny Marcum | Golden Buddhas | 2.25 |
| Mace Brown | Whiffenpoofs | 2.31 |
| Lefty Grove* | Bean Brewers | 2.45 |
| Bill Lohrman | Blue Sox | 2.51 |
| Paul Derringer | Dodgers | 2.52 |
| Joe Dobson | Atlantics | 2.57 |
| Fritz Ostermueller* | Gassers | 2.82 |
| Jim Turner | Bean Brewers | 2.84 |
| Kirby Higbe | Whiffenpoofs | 2.89 |
| Whitey Moore | Atlantics | 2.91 |
| Syl Johnson | Golden Buddhas | 3.00 |
| Johnny Humphries | Titans | 3.00 |
| Bill Crouch | Colonels | 3.12 |
| Max Butcher | Frogs | 3.18 |
| Ted Lyons | Whiffenpoofs | 3.20 |
| Red Ruffing | Atlantics | 3.24 |
| Marius Russo* | Frogs | 3.24 |
| Hugh Casey | Dodgers | 3.27 |
| Curt Davis | Seals | 3.43 |
| Nels Potter | Dodgers | 3.50 |
| Milt Shoffner* | Colonels | 3.51 |
| Lefty Mills* | Whiffenpoofs | 3.55 |
| Charlie Root | Sprudels | 3.68 |
| Vern Kennedy | Titans | 3.72 |
| Danny MacFayden | Atlantics | 3.72 |
| Harry Gumbert | Blue Sox | 4.00 |
| Joe Haynes | Golden Buddhas | 4.08 |
| Steve Sundra | Mutuals | 4.11 |
| Dutch Leonard | Titans | 4.12 |
| Joe Bowman | Atlantics | 4.15 |
| Bill Swift | Frogs | 4.15 |
| Earl Whitehill* | Bean Brewers | 4.22 |
| Thornton Lee* | Glaziers | 4.30 |
| Claude Passeau | Sprudels | 4.39 |
| Jim Tobin | Frogs | 4.50 |
| Bob Bowman | Glaziers | 4.50 |
| Lynn Nelson | Seals | 4.50 |
| Harry Kimberlin | Colonels | 4.50 |
| Dick Errickson | Bean Brewers | 4.63 |
| Bucky Walters | Glaziers | 4.63 |
| Bill Trotter | Bean Brewers | 4.63 |
| Jack Kramer | Sprudels | 4.76 |
| Atley Donald | Dodgers | 4.85 |
| Gene Lillard | Titans | 5.14 |
| Paul Dean | Seals | 5.14 |
| Bill Posedel | Golden Buddhas | 5.23 |
| Lee Grissom* | Gassers | 5.29 |
| John Whitehead | Gassers | 5.40 |
| George Caster | Golden Buddhas | 5.40 |
| Freddy Fitzsimmons | Colonels | 5.40 |
| Cliff Melton* | Blue Sox | 5.48 |
| Bob Klinger | Colonels | 5.68 |
| Johnny Allen | Atlantics | 5.71 |
| Dizzy Dean | Sprudels | 5.79 |
| Buck Ross | Golden Buddhas | 5.82 |
| Tot Pressnell | Mutuals | 5.94 |
| Bill Lee | Titans | 6.10 |
| Bob Feller | Blue Sox | 6.23 |
| Eddie Smith* | Gassers | 6.27 |
| Johnny Broaca | Sprudels | 6.35 |
| Bill Beckmann | Golden Buddhas | 6.48 |
| Bobo Newsom | Glaziers | 6.48 |
| Bob Harris | Gassers | 6.57 |
| Lou Fette | Colonels | 6.59 |
| Clyde Shoun* | Titans | 7.04 |
| Oral Hildebrand | Gassers | 7.45 |
| Manny Salvo | Whiffenpoofs | 7.50 |
| Ira Hutchinson | Mutuals | 7.56 |
| Clint Brown | Frogs | 7.88 |
| Boom-Boom Beck | Sprudels | 8.03 |
| Lon Warneke | Whiffenpoofs | 8.80 |
| Ken Chase* | Bean Brewers | 8.80 |
| Joe Heving | Whiffenpoofs | 9.31 |
| Whit Wyatt | Golden Buddhas | 9.39 |
| Mel Harder | Bean Brewers | 9.58 |
| Walt Masterson | Sprudels | 9.72 |
| Hal Schumacher | Frogs | 9.72 |
| Slick Castleman | Blue Sox | 10.13 |
| Mort Cooper | Seals | 10.13 |
| Jake Wade* | Gassers | 10.50 |
| Ken Heintzelman* | Frogs | 14.14 |